Mir-216-P2

MirGeneDB ID

Aga-Mir-216-P2

Family name

MIR-216 (all species)

Species

African malaria mosquito (Anopheles gambiae)

MiRBase ID

aga-mir-1889

Paralogues

Aga-Mir-216-P1

Orthologues

Aae-Mir-216-P2 Aca-Mir-216-P2a Aca-Mir-216-P2b Agr-Mir-216-P2c Agr-Mir-216-P2d Ami-Mir-216-P2a Ami-Mir-216-P2b Asu-Mir-216-P2 Ava-Mir-216-P2 Bfl-Mir-216-P2 Bge-Mir-216-P2 Bko-Mir-216-P2 Bla-Mir-216-P2 Bpl-Mir-216-P2 Bta-Mir-216-P2a Bta-Mir-216-P2b Cbr-Mir-216-P2 Cel-Mir-216-P2 Cfa-Mir-216-P2a Cfa-Mir-216-P2b Cja-Mir-216-P2a Cja-Mir-216-P2b Cli-Mir-216-P2a Cli-Mir-216-P2b Cmi-Mir-216-P2a Cmi-Mir-216-P2b Cpi-Mir-216-P2a Cpi-Mir-216-P2b Cpo-Mir-216-P2a Cpo-Mir-216-P2b Csc-Mir-216-P2 Cte-Mir-216-P2c Cte-Mir-216-P2d Dan-Mir-216-P2 Dgr-Mir-216-P2c Dlo-Mir-216-P2 Dma-Mir-216-P2 Dme-Mir-216-P2 Dmo-Mir-216-P2 Dno-Mir-216-P2a Dno-Mir-216-P2b Dpu-Mir-216-P2 Dre-Mir-216-P2a Dre-Mir-216-P2b Dsi-Mir-216-P2 Dya-Mir-216-P2 Eba-Mir-216-P2c Ebu-Mir-216-P2a2 Ebu-Mir-216-P2b1 Eca-Mir-216-P2a Eca-Mir-216-P2b Efe-Mir-216-P2c Esc-Mir-216-P2d Ete-Mir-216-P2a Ete-Mir-216-P2b Gga-Mir-216-P2a Gga-Mir-216-P2b Gja-Mir-216-P2a Gja-Mir-216-P2b Gmo-Mir-216-P2a Gmo-Mir-216-P2b Hme-Mir-216-P2 Hru-Mir-216-P2d Hsa-Mir-216-P2a Hsa-Mir-216-P2b Isc-Mir-216-P2 Laf-Mir-216-P2a Laf-Mir-216-P2b Lan-Mir-216-P2d1 Lan-Mir-216-P2d2 Lch-Mir-216-P2a Lch-Mir-216-P2b Lgi-Mir-216-P2d Lhy-Mir-216-P2c Lhy-Mir-216-P2d Llo-Mir-216-P2c Llo-Mir-216-P2d Loc-Mir-216-P2a Loc-Mir-216-P2b Lpo-Mir-216-P2g Lpo-Mir-216-P2h Lpo-Mir-216-P2i Mal-Mir-216-P2a Mal-Mir-216-P2b Mdo-Mir-216-P2a Mdo-Mir-216-P2b Mgi-Mir-216-P2d Mml-Mir-216-P2a Mml-Mir-216-P2b Mmr-Mir-216-P2a Mmr-Mir-216-P2b Mmu-Mir-216-P2a Mmu-Mir-216-P2b Mom-Mir-216-P2c Mom-Mir-216-P2d Mun-Mir-216-P2b Neu-Mir-216-P2a Neu-Mir-216-P2b Npo-Mir-216-P2c Npo-Mir-216-P2d Oan-Mir-216-P2a Oan-Mir-216-P2b Obi-Mir-216-P2c Obi-Mir-216-P2d Ocu-Mir-216-P2a Ocu-Mir-216-P2b Ofu-Mir-216-P2c Ofu-Mir-216-P2d Ovu-Mir-216-P2c Ovu-Mir-216-P2d Pab-Mir-216-P2a Pab-Mir-216-P2b Pau-Mir-216-P2c Pau-Mir-216-P2d Pbv-Mir-216-P2a Pbv-Mir-216-P2b Pca-Mir-216-P2 Pcr-Mir-216-P2o1-v1 Pcr-Mir-216-P2o2 Pdu-Mir-216-P2d Pma-Mir-216-P2a1 Pma-Mir-216-P2a2 Pma-Mir-216-P2b1 Pve-Mir-216-P2d Rno-Mir-216-P2a Rno-Mir-216-P2b Rph-Mir-216-P2d Sha-Mir-216-P2a Sha-Mir-216-P2b Sme-Mir-216-P2e Sme-Mir-216-P2f Snu-Mir-216-P2c Snu-Mir-216-P2d Spt-Mir-216-P2a Spt-Mir-216-P2b Sto-Mir-216-P2a Sto-Mir-216-P2b Tca-Mir-216-P2 Tgu-Mir-216-P2a Tgu-Mir-216-P2b Tni-Mir-216-P2a Tni-Mir-216-P2b Tur-Mir-216-P2 War-Mir-216-P2c Xla-Mir-216-P2b3 Xla-Mir-216-P2b4 Xtr-Mir-216-P2b

Node of Origin (locus)

Nephrozoa

Node of Origin (family)

Nephrozoa

Genome context
(GCF_943734735.2_idAnoGambNW_F1_1_genomic)

NC_064601.1: 37380031-37380129 [-] Ensembl

Clustered miRNAs
(< 50kb from Mir-216-P2)

Mir-12 NC_064601.1: 37379265-37379375 [-] Ensembl
Mir-216-P2 NC_064601.1: 37380031-37380129 [-] Ensembl
Mir-216-P1 NC_064601.1: 37381281-37381346 [-] Ensembl

Seed

AAUCUCA

Precursor
(pre-Mir +30nt flank)

ACACACACACAUUGUGGCGUGGAUGGGCGGCAAUCUCAAAUUGUAAUAGUGUGUCACCGUUAACGGCUGGACCAUUGUGCUGCCAUCGUGAUCCACCGAGAAAAACACACAUUACAGAUUGGGAUUACCCCGUCCAUGCUCCGCUCACCACAUACAACC

Get precursor sequence

Structure

        10            20        30        40        50        60        70         
ACACACACACAUUGUGG----|         CGGC        A       A      CACCGUUAACGGCUGGACCAUUGU 
                     CGUGGAUGGG    AAUCUCAA UUGUAAU GUGUGU                        G
                     GUACCUGCCC    UUAGGGUU GACAUUA CACACA                        C
CCAACAUACACCACUCGCCUC^         CA--        A       -      AAAAGAGCCACCUAGUGCUACCGU 
       150       140       130         120        110       100        90        80

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut -1 on both arms.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ab	Ab	He	He	Mi	Mi	Ov	Ov	Ov

Mature sequence

Aga-Mir-216-P2_5p

mirBase accession

None

Sequence

0- CAAUCUCAAAUUGUAAUAGUGUGU -24

Get sequence

Star sequence

Aga-Mir-216-P2_3p*

mirBase accession

MIMAT0007859

Sequence

76- ACACAUUACAGAUUGGGAUUACC -99

Get sequence