Mir-17-P1c

MirGeneDB ID

Rno-Mir-17-P1c

Family name

MIR-17 (all species)

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-17-2

Paralogues

Rno-Mir-17-P1a Rno-Mir-17-P1d Rno-Mir-17-P2a Rno-Mir-17-P2c Rno-Mir-17-P4a Rno-Mir-17-P4c Rno-Mir-17-P4d

Orthologues

Aca-Mir-17-P1c Ami-Mir-17-P1c Bta-Mir-17-P1c Cfa-Mir-17-P1c Cja-Mir-17-P1c Cli-Mir-17-P1c Cmi-Mir-17-P1c Cpi-Mir-17-P1c Cpo-Mir-17-P1c Dno-Mir-17-P1c Eca-Mir-17-P1c Ete-Mir-17-P1c Gga-Mir-17-P1c Gja-Mir-17-P1c Hsa-Mir-17-P1c Laf-Mir-17-P1c Lch-Mir-17-P1c Loc-Mir-17-P1c Mdo-Mir-17-P1c Mml-Mir-17-P1c Mmr-Mir-17-P1c Mmu-Mir-17-P1c Mun-Mir-17-P1c Neu-Mir-17-P1c Oan-Mir-17-P1c Ocu-Mir-17-P1c Pab-Mir-17-P1c Pbv-Mir-17-P1c Sha-Mir-17-P1c Spt-Mir-17-P1c Sto-Mir-17-P1c Tgu-Mir-17-P1c Xla-Mir-17-P1c3 Xla-Mir-17-P1c4 Xtr-Mir-17-P1c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(rn6)

chrX: 140117900-140117958 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-17-P1c)

Mir-92-P2c chrX: 140117108-140117172 [-] UCSC Ensembl
Mir-92-P1c chrX: 140117265-140117325 [-] UCSC Ensembl
Mir-19-P2c chrX: 140117391-140117456 [-] UCSC Ensembl
Mir-17-P4c chrX: 140117522-140117582 [-] UCSC Ensembl
Mir-17-P2c chrX: 140117734-140117798 [-] UCSC Ensembl
Mir-17-P1c chrX: 140117900-140117958 [-] UCSC Ensembl

Seed

AAAGUGC

Precursor
(pre-Mir +30nt flank)

UUACACUGCUGGAACAUGCCUUGGCCAUGUCAAAGUGCUUACAGUGCAGGUAGCUUCUUGAGAUCUACUGCACUGCAAGCACUUCUUACAUUACCAUGGUGAUUUAAUCAGAGGCCACU

Get precursor sequence

Structure

        10          20        30         40        50         
UUACACUGCUGGAACAU--   U   CC    CA-|       A        G   CUUCU 
                   GCC UGG  AUGU   AAGUGCUU CAGUGCAG UAG     \
                   UGG ACC  UACA   UUCACGAA GUCACGUC AUC     U
UCACCGGAGACUAAUUUAG   U   AU    UUC^       C        -   UAGAG 
       110       100        90        80        70         60

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut +1 on the 3p arm.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Mir-17-P1c_5p

mirBase accession

MIMAT0000786

Sequence

0- CAAAGUGCUUACAGUGCAGGUAG -23

Get sequence

Proposed targets

microrna.org: MIMAT0000786
TargetScanVert: rno-miR-17-5p
miRDB: MIMAT0000786

Star sequence

Rno-Mir-17-P1c_3p*

mirBase accession

MIMAT0017295

Sequence

36- ACUGCACUGCAAGCACUUCUUAC -59

Get sequence

Proposed targets

TargetScanVert: rno-miR-17-2-3p
miRDB: MIMAT0017295