Mir-17-P4a

MirGeneDB ID

Hsa-Mir-17-P4a

Family name

MIR-17 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-20a

Paralogues

Hsa-Mir-17-P1a Hsa-Mir-17-P1c Hsa-Mir-17-P1d Hsa-Mir-17-P2a Hsa-Mir-17-P2c Hsa-Mir-17-P4c Hsa-Mir-17-P4d

Orthologues

Aca-Mir-17-P4a Ami-Mir-17-P4a Bta-Mir-17-P4a Cfa-Mir-17-P4a Cja-Mir-17-P4a Cli-Mir-17-P4a Cmi-Mir-17-P4a Cpi-Mir-17-P4a Cpo-Mir-17-P4a Dno-Mir-17-P4a Dre-Mir-17-P4a1 Dre-Mir-17-P4a2 Eca-Mir-17-P4a Ete-Mir-17-P4a Gga-Mir-17-P4a Gja-Mir-17-P4a Gmo-Mir-17-P4a1 Gmo-Mir-17-P4a2 Laf-Mir-17-P4a Lch-Mir-17-P4a Loc-Mir-17-P4a Mal-Mir-17-P4a1 Mal-Mir-17-P4a2 Mdo-Mir-17-P4a Mml-Mir-17-P4a Mmr-Mir-17-P4a Mmu-Mir-17-P4a Mun-Mir-17-P4a Neu-Mir-17-P4a Oan-Mir-17-P4a7 Oan-Mir-17-P4a8 Ocu-Mir-17-P4a Pab-Mir-17-P4a Pbv-Mir-17-P4a Rno-Mir-17-P4a Sha-Mir-17-P4a Spt-Mir-17-P4a Sto-Mir-17-P4a Tgu-Mir-17-P4a Tni-Mir-17-P4a1 Tni-Mir-17-P4a2 Xla-Mir-17-P4a3 Xla-Mir-17-P4a4 Xtr-Mir-17-P4a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr13: 91351072-91351130 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-17-P4a)

Mir-17-P1a chr13: 91350618-91350677 [+] UCSC Ensembl
Mir-17-P2a chr13: 91350756-91350820 [+] UCSC Ensembl
Mir-19-P1a chr13: 91350904-91350961 [+] UCSC Ensembl
Mir-17-P4a chr13: 91351072-91351130 [+] UCSC Ensembl
Mir-19-P2a chr13: 91351207-91351267 [+] UCSC Ensembl
Mir-92-P1a chr13: 91351324-91351382 [+] UCSC Ensembl

Seed

AAAGUGC

Precursor
(pre-Mir +30nt flank)

GUCUAUCUGAUGUGACAGCUUCUGUAGCACUAAAGUGCUUAUAGUGCAGGUAGUGUUUAGUUAUCUACUGCAUUAUGAGCACUUAAAGUACUGCUAGCUGUAGAACUCCAGCUUCGGCC

Get precursor sequence

Structure

        10            20        30         40        50         
GUCUAUCUGAUGUGACA----|  UCU    C   A-                 G   UGUUU 
                     GCU   GUAG ACU  AAGUGCUUAUAGUGCAG UAG     \
                     CGA   CGUC UGA  UUCACGAGUAUUACGUC AUC     A
CCGGCUUCGACCUCAAGAUGU^  U--    A   AA                 -   UAUUG 
       110       100          90        80        70         60

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut -1 on both arms.

3' NTU

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-17-P4a_5p

mirBase accession

MIMAT0000075

Sequence

0- UAAAGUGCUUAUAGUGCAGGUAG -23

Get sequence

Proposed targets

microrna.org: MIMAT0000075
TargetScanVert: hsa-miR-20a-5p
TargetMiner: hsa-miR-20a-5p
miRDB: MIMAT0000075

Star sequence

Hsa-Mir-17-P4a_3p*

mirBase accession

MIMAT0004493

Sequence

36- ACUGCAUUAUGAGCACUUAAAGU -59

Get sequence

Proposed targets

microrna.org: MIMAT0004493
TargetScanVert: hsa-miR-20a-3p
TargetMiner: hsa-miR-20a-3p
miRDB: MIMAT0004493