Mir-17-P2c

MirGeneDB ID

Hsa-Mir-17-P2c

Family name

MIR-17 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-18b

Paralogues

Hsa-Mir-17-P1a Hsa-Mir-17-P1c Hsa-Mir-17-P1d Hsa-Mir-17-P2a Hsa-Mir-17-P4a Hsa-Mir-17-P4c Hsa-Mir-17-P4d

Orthologues

Aca-Mir-17-P2c Ami-Mir-17-P2c Bta-Mir-17-P2c Cfa-Mir-17-P2c Cja-Mir-17-P2c Cli-Mir-17-P2c Cmi-Mir-17-P2c Cpi-Mir-17-P2c Cpo-Mir-17-P2c Dno-Mir-17-P2c Dre-Mir-17-P2c Eca-Mir-17-P2c Ete-Mir-17-P2c Gga-Mir-17-P2c Gja-Mir-17-P2c Gmo-Mir-17-P2c Laf-Mir-17-P2c Lch-Mir-17-P2c Loc-Mir-17-P2c Mdo-Mir-17-P2c Mml-Mir-17-P2c Mmr-Mir-17-P2c Mmu-Mir-17-P2c Mun-Mir-17-P2c Neu-Mir-17-P2c Oan-Mir-17-P2c Ocu-Mir-17-P2c Pab-Mir-17-P2c Pbv-Mir-17-P2c Rno-Mir-17-P2c Sha-Mir-17-P2c Spt-Mir-17-P2c Sto-Mir-17-P2c Tgu-Mir-17-P2c Xla-Mir-17-P2c3 Xla-Mir-17-P2c4 Xtr-Mir-17-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chrX: 134170042-134170106 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-17-P2c)

Mir-92-P2c chrX: 134169382-134169446 [-] UCSC Ensembl
Mir-92-P1c chrX: 134169544-134169604 [-] UCSC Ensembl
Mir-19-P2c chrX: 134169683-134169748 [-] UCSC Ensembl
Mir-17-P4c chrX: 134169812-134169872 [-] UCSC Ensembl
Mir-17-P2c chrX: 134170042-134170106 [-] UCSC Ensembl
Mir-17-P1c chrX: 134170208-134170266 [-] UCSC Ensembl

Seed

AAGGUGC

Precursor
(pre-Mir +30nt flank)

GAGCUGCUUCUUAUAAUGUGUCUCUUGUGUUAAGGUGCAUCUAGUGCAGUUAGUGAAGCAGCUUAGAAUCUACUGCCCUAAAUGCCCCUUCUGGCACAGGCUGCCUAAUAUACAGCAUUUUAAAA

Get precursor sequence

Structure

        10          20        30          40        50        60 
GAGCUGCUUCUUAUAAUGU--  CU         --|  U    C   U     UA  GAAGCA 
                     GU  CUUGUGUUA  AGG GCAU UAG GCAGU  GU      \
                     CG  GGACACGGU  UCC CGUA AUC CGUCA  UA      G
AAAAUUUUACGACAUAUAAUC  UC         CU^  C    A   C     UC  AGAUUC 
   120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-17-P2c_5p

mirBase accession

MIMAT0001412

Sequence

0- UAAGGUGCAUCUAGUGCAGUUAGU -24

Get sequence

Proposed targets

microrna.org: MIMAT0001412
TargetScanVert: hsa-miR-18b-5p
TargetMiner: hsa-miR-18b-5p
miRDB: MIMAT0001412

Star sequence

Hsa-Mir-17-P2c_3p*

mirBase accession

MIMAT0004751

Sequence

40- UACUGCCCUAAAUGCCCCUUCUGGC -65

Get sequence

Proposed targets

microrna.org: MIMAT0004751
TargetScanVert: hsa-miR-18b-3p
TargetMiner: hsa-miR-18b-3p
miRDB: MIMAT0004751