Mir-219-P2b

MirGeneDB ID

Dre-Mir-219-P2b

Family name

MIR-219 (all species)

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-mir-219-2

Paralogues

Dre-Mir-219-P2a Dre-Mir-219-P3a

Orthologues

Aae-Mir-219 Aca-Mir-219-P2 Aga-Mir-219 Agr-Mir-219 Ami-Mir-219-P2 Bfl-Mir-219 Bge-Mir-219 Bko-Mir-219 Bla-Mir-219 Bpl-Mir-219 Bta-Mir-219-P2 Bta-Mir-219-P2-as Cfa-Mir-219-P2 Cfa-Mir-219-P2-as Cin-Mir-219 Cja-Mir-219-P2 Cli-Mir-219-P2 Cmi-Mir-219-P2 Cpi-Mir-219-P2 Cpo-Mir-219-P2 Cpo-Mir-219-P2-as Csc-Mir-219 Cte-Mir-219 Dan-Mir-219 Dgr-Mir-219 Dlo-Mir-219 Dma-Mir-219 Dme-Mir-219 Dmo-Mir-219 Dno-Mir-219-P2 Dno-Mir-219-P2-as Dpu-Mir-219 Dsi-Mir-219 Dya-Mir-219 Eba-Mir-219 Eca-Mir-219-P2 Egr-Mir-219 Esc-Mir-219 Ete-Mir-219-P2 Gga-Mir-219-P2 Gja-Mir-219-P2 Gpa-Mir-219 Gsa-Mir-219 Gsp-Mir-219 Hmi-Mir-219 Hru-Mir-219 Hsa-Mir-219-P2 Hsa-Mir-219-P2-as Isc-Mir-219 Laf-Mir-219-P2 Lan-Mir-219 Lch-Mir-219-P2 Llo-Mir-219 Loc-Mir-219-P2 Mal-Mir-219-P2b Mdo-Mir-219-P2 Mgi-Mir-219 Mml-Mir-219-P2 Mml-Mir-219-P2-as Mmr-Mir-219-P2 Mmu-Mir-219-P2 Mmu-Mir-219-P2-as Mom-Mir-219 Mun-Mir-219-P2 Neu-Mir-219-P2 Oan-Mir-219-P2 Obi-Mir-219 Ocu-Mir-219-P2 Ocu-Mir-219-P2-as Ofu-Mir-219 Ovu-Mir-219 Pab-Mir-219-P2 Pab-Mir-219-P2-as Pau-Mir-219 Pbv-Mir-219-P2 Pca-Mir-219 Pcr-Mir-219 Pfl-Mir-219 Pma-Mir-219-o2 Pmi-Mir-219 Pve-Mir-219 Rno-Mir-219-P2 Rno-Mir-219-P2-as Rph-Mir-219 Sha-Mir-219-P2 Sko-Mir-219 Sma-Mir-219 Sne-Mir-219 Snu-Mir-219 Spt-Mir-219-P2 Spu-Mir-219 Sro-Mir-219 Sto-Mir-219-P2 Tca-Mir-219 Tgu-Mir-219-P2 Tni-Mir-219-P2b Tur-Mir-219 War-Mir-219 Xbo-Mir-219 Xtr-Mir-219-P2

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Bilateria

Genome context
(danRer11)

chr5: 65101371-65101437 [+] UCSC Ensembl

Seed

GAUUGUC

Precursor
(pre-Mir +30nt flank)

UUUUUUUGUGGAAAUUUGAGCUCAAGCAGUUGAUUGUCCAAACGCAAUUCUUGUGAAAUGUCGAGCGAUCAGUCGAGAAUUGUGCCUGGACAUCUGUUGCUGGAGGCUCCACGCGACUCAUCAUCAU

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Structure

        10         20         30        40        50        60   
UUUUUUUGUGGAAAUUU-   -|  A     UU   U     AA           UGAAAUGUC 
                  GAG CUC AGCAG  GAU GUCCA  CGCAAUUCUUG         G
                  CUC GAG UCGUU  CUA CAGGU  GUGUUAAGAGC         A
UACUACUACUCAGCGCAC   G^  G     GU   -     CC           UGACUAGCG 
     120       110       100         90        80        70

Deep sequencing

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Comment

The MIR-219 family shows substantial variation of arm-usage and is currently, across all species, considered a co-mature.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Mature sequence

Dre-Mir-219-P2b_5p

mirBase accession

MIMAT0001286

Sequence

0- UGAUUGUCCAAACGCAAUUCUUG -23

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Proposed targets

TargetScanFish: dre-miR-219

Co-mature sequence

Dre-Mir-219-P2b_3p

mirBase accession

None

Sequence

45- AGAAUUGUGCCUGGACAUCUGU -67

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