Mir-219-P3a

MirGeneDB ID

Dre-Mir-219-P3a

Family name

MIR-219 (all species)

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-mir-219-3

Paralogues

Dre-Mir-219-P2a Dre-Mir-219-P2b

Orthologues

Aae-Mir-219 Aca-Mir-219-P3 Aga-Mir-219 Agr-Mir-219 Ami-Mir-219-P3 Bfl-Mir-219 Bge-Mir-219 Bko-Mir-219 Bla-Mir-219 Bpl-Mir-219 Bta-Mir-219-P3 Cfa-Mir-219-P3 Cin-Mir-219 Cja-Mir-219-P3 Cmi-Mir-219-P3 Cpi-Mir-219-P3 Cpo-Mir-219-P3 Csc-Mir-219 Cte-Mir-219 Dan-Mir-219 Dgr-Mir-219 Dlo-Mir-219 Dma-Mir-219 Dme-Mir-219 Dmo-Mir-219 Dno-Mir-219-P3 Dpu-Mir-219 Dsi-Mir-219 Dya-Mir-219 Eba-Mir-219 Eca-Mir-219-P3 Egr-Mir-219 Esc-Mir-219 Ete-Mir-219-P3 Gja-Mir-219-P3 Gmo-Mir-219-P3a Gpa-Mir-219 Gsa-Mir-219 Gsp-Mir-219 Hmi-Mir-219 Hru-Mir-219 Hsa-Mir-219-P3 Isc-Mir-219 Laf-Mir-219-P3 Lan-Mir-219 Lch-Mir-219-P3 Llo-Mir-219 Mal-Mir-219-P3a Mdo-Mir-219-P3 Mgi-Mir-219 Mml-Mir-219-P3 Mmr-Mir-219-P3 Mmu-Mir-219-P3 Mmu-Mir-219-P3-as Mom-Mir-219 Mun-Mir-219-P3-v1 Neu-Mir-219-P3 Obi-Mir-219 Ocu-Mir-219-P3 Ofu-Mir-219 Ovu-Mir-219 Pab-Mir-219-P3 Pau-Mir-219 Pbv-Mir-219-P3 Pca-Mir-219 Pcr-Mir-219 Pfl-Mir-219 Pmi-Mir-219 Pve-Mir-219 Rno-Mir-219-P3 Rph-Mir-219 Sha-Mir-219-P3 Sko-Mir-219 Sma-Mir-219 Sne-Mir-219 Snu-Mir-219 Spt-Mir-219-P3 Spu-Mir-219 Sro-Mir-219 Sto-Mir-219-P3-v1 Tca-Mir-219 Tni-Mir-219-P3a Tur-Mir-219 War-Mir-219 Xbo-Mir-219

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Bilateria

Genome context
(danRer11)

chr19: 18861780-18861840 [-] UCSC Ensembl

Seed

GAUUGUC

Precursor
(pre-Mir +30nt flank)

CUGUCUGGUUUGAUACUGACGGUCAGGUGCUGAUUGUCCAAACGCAAUUCUUGUGCUUGUGUGAAACAGGAGUUGUGGAUGGACAUCACGCUCCUGUCUGGUCCUCACAUCUACAGGAUGG

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Structure

        10          20        30         40        50          
CUGUCUGGUUUGAUACUGA--   U    U  -|   U     AA           UGCUUG 
                     CGG CAGG GC UGAU GUCCA  CGCAAUUCUUG      \
                     GUC GUCC CG ACUA CAGGU  GUGUUGAGGAC      U
GGUAGGACAUCUACACUCCUG   U    U  C^   -     AG           AAAGUG 
 .       110       100        90         80        70

Deep sequencing

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Comment

The MIR-219 family shows substantial variation of arm-usage and is currently, across all species, considered a co-mature.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Mature sequence

Dre-Mir-219-P3a_5p

mirBase accession

MIMAT0001286

Sequence

0- UGAUUGUCCAAACGCAAUUCUUG -23

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Proposed targets

TargetScanFish: dre-miR-219

Co-mature sequence

Dre-Mir-219-P3a_3p

mirBase accession

MIMAT0031989

Sequence

38- GGAGUUGUGGAUGGACAUCACGC -61

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