MirGeneDB 3.0

MirGeneDB ID

Llo-Mir-2-P12

Family name MIR-2 (all species)
Species Bootlace worm (Lineus longissimus)
MiRBase ID
Paralogues Llo-Mir-2-o114-v1  Llo-Mir-2-o115  Llo-Mir-2-o116  Llo-Mir-2-o117  Llo-Mir-2-o118  Llo-Mir-2-o119  Llo-Mir-2-o120  Llo-Mir-2-o121 
Orthologues Agr-Mir-2-P12a  Agr-Mir-2-P12b  Agr-Mir-2-P12c  Agr-Mir-2-P12d  Agr-Mir-2-P12e  Agr-Mir-2-P12f1  Agr-Mir-2-P12f2  Cte-Mir-2-P12  Dgr-Mir-2-P12  Efe-Mir-2-P12f  Efe-Mir-2-P12g  Esc-Mir-2-P12  Gsp-Mir-2  Hru-Mir-2-P12  Lgi-Mir-2-P12a  Lgi-Mir-2-P12b  Lgi-Mir-2-P12c  Lgi-Mir-2-P12d  Lgi-Mir-2-P12e  Lhy-Mir-2-P12  Mgi-Mir-2-P12  Mom-Mir-2-P12f  Mom-Mir-2-P12g  Mom-Mir-2-P12h  Mom-Mir-2-P12i  Mom-Mir-2-P12j  Mom-Mir-2-P12k  Npo-Mir-2-P12  Obi-Mir-2-P12  Ofu-Mir-2-P12  Ovu-Mir-2-P12  Pau-Mir-2-P12  Pdu-Mir-2-P12  Ple-Mir-2  Pve-Mir-2-P12  Rph-Mir-2-P12  War-Mir-2-P12 
Node of Origin (locus) Lophotrochozoa
Node of Origin (family) Protostomia
Genome context
(GCA_910592395.2_tnLinLong1)
OU343002.1: 11596059-11596116 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-P12)
Mir-2-o117 OU343002.1: 11593640-11593697 [-] Ensembl
Mir-2-o116 OU343002.1: 11594484-11594542 [-] Ensembl
Mir-2-o115 OU343002.1: 11595818-11595877 [-] Ensembl
Mir-2-P12 OU343002.1: 11596059-11596116 [-] Ensembl
Mir-2-o114-v1 OU343002.1: 11598646-11598704 [-] Ensembl
Mir-2-o114-v2 OU343002.1: 11598647-11598703 [-] Ensembl
Mir-71 OU343002.1: 11598853-11598911 [-] Ensembl
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
GAUCGUCAGUGAUGAGGUGGUGUCUGCCUCCGAUUCAAGUGGCUGUGAUGUGUUACAACAAGUCAUAUCACAGCCUGCUUGGAUUAGAGGCUGGUGCUAGGAGAAUUACUGGCUAAUG
Get precursor sequence
Structure
        10          20        30        40         50        
GAUCGUCAGUGAUGAGG--   UG  U     CG        -|           UUACA 
                   UGG  UC GCCUC  AUUCAAGU GGCUGUGAUGUG     \
                   AUC  GG CGGAG  UAGGUUCG CCGACACUAUAC     A
GUAAUCGGUCAUUAAGAGG   GU  U     AU        U^           UGAAC 
      110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsNo
Tissue expression
- +
No No No No No No
Star sequence

Llo-Mir-2-P12_5p*

mirBase accessionNone
Sequence
0- CGAUUCAAGUGGCUGUGAUGUG -22
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Mature sequence

Llo-Mir-2-P12_3p

mirBase accessionNone
Sequence
35- UAUCACAGCCUGCUUGGAUUAGA -58
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