MirGeneDB 3.0

MirGeneDB ID

Hru-Mir-2-P12

Family name MIR-2 (all species)
Species Red Abalone (Haliotis rufescens)
MiRBase ID
Paralogues Hru-Mir-2-o51  Hru-Mir-2-o52  Hru-Mir-2-o53  Hru-Mir-2-o54  Hru-Mir-2-o55 
Orthologues Agr-Mir-2-P12a  Agr-Mir-2-P12b  Agr-Mir-2-P12c  Agr-Mir-2-P12d  Agr-Mir-2-P12e  Agr-Mir-2-P12f1  Agr-Mir-2-P12f2  Cte-Mir-2-P12  Dgr-Mir-2-P12  Efe-Mir-2-P12f  Efe-Mir-2-P12g  Esc-Mir-2-P12  Gsp-Mir-2  Lgi-Mir-2-P12a  Lgi-Mir-2-P12b  Lgi-Mir-2-P12c  Lgi-Mir-2-P12d  Lgi-Mir-2-P12e  Lhy-Mir-2-P12  Llo-Mir-2-P12  Mgi-Mir-2-P12  Mom-Mir-2-P12f  Mom-Mir-2-P12g  Mom-Mir-2-P12h  Mom-Mir-2-P12i  Mom-Mir-2-P12j  Mom-Mir-2-P12k  Npo-Mir-2-P12  Obi-Mir-2-P12  Ofu-Mir-2-P12  Ovu-Mir-2-P12  Pau-Mir-2-P12  Pdu-Mir-2-P12  Ple-Mir-2  Pve-Mir-2-P12  Rph-Mir-2-P12  War-Mir-2-P12 
Node of Origin (locus) Lophotrochozoa
Node of Origin (family) Protostomia
Genome context
(GCA_023055435.1_xgHalRufe1.0.p_genomic_plus_traces)
JALGQA010000019.1: 17033706-17033763 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-2-P12)
Mir-71 JALGQA010000019.1: 17032907-17032964 [+] UCSC Ensembl
Mir-2-o55 JALGQA010000019.1: 17033087-17033148 [+] UCSC Ensembl
Mir-2-P12 JALGQA010000019.1: 17033706-17033763 [+] UCSC Ensembl
Mir-2-o51 JALGQA010000019.1: 17033823-17033880 [+] UCSC Ensembl
Mir-2-o52 JALGQA010000019.1: 17033972-17034029 [+] UCSC Ensembl
Mir-2-o53 JALGQA010000019.1: 17034102-17034159 [+] UCSC Ensembl
Mir-2-o54 JALGQA010000019.1: 17034273-17034331 [+] UCSC Ensembl
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
ACUGACAGAUUCUUCAGAAGUAUGCCACUUCUGACCAGGUGGUUGGGAUGUGUUGUACAAGCCAUAUCACAGCCUGCUUGGAUCAGUAGUGUUGUAUUGGUCGCAGCCAGUUGAAAGA
Get precursor sequence
Structure
        10          20        30         40         50       
ACUGACAGAUUCUUCAGA--     GC    U    -      -|    G      UUGU 
                    AGUAU  CACU CUGA CCAGGU GGUUG GAUGUG    A
                    UUAUG  GUGA GACU GGUUCG CCGAC CUAUAC    C
AGAAAGUUGACCGACGCUGG     UU    U    A      U^    A      CGAA 
      110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsCNNC at 3p(+17)
Tissue expression
- +
To To
Star sequence

Hru-Mir-2-P12_5p* (predicted)

mirBase accessionNone
Sequence
0- CUGACCAGGUGGUUGGGAUGUG -22
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Mature sequence

Hru-Mir-2-P12_3p

mirBase accessionNone
Sequence
34- UAUCACAGCCUGCUUGGAUCAGUA -58
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