MirGeneDB 3.0

MirGeneDB ID

Llo-Mir-2-o121

Family name MIR-2 (all species)
Species Bootlace worm (Lineus longissimus)
MiRBase ID
Paralogues Llo-Mir-2-o114-v1  Llo-Mir-2-o115  Llo-Mir-2-o116  Llo-Mir-2-o117  Llo-Mir-2-o118  Llo-Mir-2-o119  Llo-Mir-2-o120  Llo-Mir-2-P12 
Orthologues Gsp-Mir-2  Ple-Mir-2 
Node of Origin (locus) Lineidae
Node of Origin (family) Protostomia
Genome context
(GCA_910592395.2_tnLinLong1)
OU343000.1: 4140571-4140629 [+] Ensembl
Clustered miRNAs
(< 50kb from Mir-2-o121)
Mir-2-o121 OU343000.1: 4140571-4140629 [+] Ensembl
Mir-2-o120 OU343000.1: 4140870-4140930 [+] Ensembl
Mir-2-o119 OU343000.1: 4142150-4142210 [+] Ensembl
Mir-2-o118 OU343000.1: 4142445-4142502 [+] Ensembl
Seed AUCACAG
Precursor
(pre-Mir +30nt flank)
UCGUGAACACAUCCUAUGCUUGUCCCUUCUUCCACAAAGUGGUUGUGAUUUGCUUCAUGUAAUCAUAUCACAGCCUGCUUUGAUGGGCUAAGUGACCGGUGAAUAACUUCUUUAGACUG
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Structure
        10          20        30         40         50        
UCGUGAACACAUCCUAU--   U   C   CU    -      -|        U  CUUCA 
                   GCU GUC CUU  UCCA CAAAGU GGUUGUGAU UG     \
                   UGG CAG GAA  GGGU GUUUCG CCGACACUA AC     U
GUCAGAUUUCUUCAAUAAG   C   U   UC    A      U^        U  UAAUG 
       110       100        90        80        70        60
Deep sequencing
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CommentIt is not clear either from phylogenetic or syntenic information how many Mir-2 genes were present in the last common ancestor of protostomes and how the multiple paralogues in lophotrochozoans relate to the four Mir-2 genes in arthropods. Thus all lophotrochozoan genes aside from Mir-2-P12 are classified as orphans pending further data and analysis.
3' NTU No
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
- +
No No No No No No
Star sequence

Llo-Mir-2-o121_5p*

mirBase accessionNone
Sequence
0- UCCACAAAGUGGUUGUGAUUUG -22
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Mature sequence

Llo-Mir-2-o121_3p

mirBase accessionNone
Sequence
35- UAUCACAGCCUGCUUUGAUGGGCU -59
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