Mir-34-P3b

MirGeneDB ID

Hsa-Mir-34-P3b

Family name

MIR-34 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-449b

Paralogues

Hsa-Mir-34-P1 Hsa-Mir-34-P2a Hsa-Mir-34-P2b Hsa-Mir-34-P3a-v1 Hsa-Mir-34-P3c

Orthologues

Aae-Mir-34 Aga-Mir-34 Agr-Mir-34 Ami-Mir-34-P3b Asu-Mir-34 Bge-Mir-34 Bta-Mir-34-P3b Cbr-Mir-34 Cel-Mir-34 Cfa-Mir-34-P3b Cin-Mir-34 Cja-Mir-34-P3b Cli-Mir-34-P3b Cmi-Mir-34-P3b Cpi-Mir-34-P3b Cte-Mir-34 Dan-Mir-34 Dlo-Mir-34 Dma-Mir-34 Dme-Mir-34 Dmo-Mir-34 Dno-Mir-34-P3b Dpu-Mir-34 Dsi-Mir-34 Dya-Mir-34 Eca-Mir-34-P3b Efe-Mir-34 Esc-Mir-34 Ete-Mir-34-P3b Gga-Mir-34-P3b Gja-Mir-34-P3b Gpa-Mir-34 Gsp-Mir-34 Hmi-Mir-34 Hru-Mir-34 Isc-Mir-34 Laf-Mir-34-P3b Lch-Mir-34-P3b Lgi-Mir-34 Lhy-Mir-34 Llo-Mir-34 Loc-Mir-34-P3b Mdo-Mir-34-P3b Mgi-Mir-34 Mml-Mir-34-P3b Mmr-Mir-34-P3b Mmu-Mir-34-P3b Mom-Mir-34 Neu-Mir-34-P3b Npo-Mir-34 Oan-Mir-34-P3b Obi-Mir-34 Ocu-Mir-34-P3b Ofu-Mir-34 Ovu-Mir-34 Pab-Mir-34-P3b Pau-Mir-34 Pbv-Mir-34-P3b Pca-Mir-34 Pdu-Mir-34 Pfl-Mir-34 Pma-Mir-34-P3 Pmi-Mir-34 Pve-Mir-34 Rno-Mir-34-P3b Rph-Mir-34 Sha-Mir-34-P3b Sko-Mir-34 Snu-Mir-34 Spt-Mir-34-P3b Spu-Mir-34 Sto-Mir-34-P3b Tca-Mir-34 Tur-Mir-34 War-Mir-34 Xla-Mir-34-P3b1 Xla-Mir-34-P3b2 Xtr-Mir-34-P3b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr5: 55170668-55170727 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-34-P3b)

Mir-34-P3c chr5: 55170546-55170607 [-] UCSC Ensembl
Mir-34-P3b chr5: 55170668-55170727 [-] UCSC Ensembl
Mir-34-P3a-v2 chr5: 55172278-55172337 [-] UCSC Ensembl
Mir-34-P3a-v1 chr5: 55172279-55172336 [-] UCSC Ensembl

Seed

GGCAGUG

Precursor
(pre-Mir +30nt flank)

CACGAGAAUCGGCAGUGACCUGAAUCAGGUAGGCAGUGUAUUGUUAGCUGGCUGCUUGGGUCAAGUCAGCAGCCACAACUACCCUGCCACUUGCUUCUGGAUAAAUUCUUCUUGUCAAUG

Get precursor sequence

Structure

        10          20        30        40         50        60  
CACGAGAAUCGGCAGUGA--| U   U     A     U   -    UAGCU       UGGGU 
                    CC GAA CAGGU GGCAG GUA UUGU     GGCUGCU     \
                    GG CUU GUUCA CCGUC CAU AACA     CCGACGA     C
GUAACUGUUCUUCUUAAAUA^ U   C     -     C   C    -----       CUGAA 
.       110       100        90         80             70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-34-P3b_5p

mirBase accession

MIMAT0003327

Sequence

0- AGGCAGUGUAUUGUUAGCUGGCUGCU -26

Get sequence

Proposed targets

microrna.org: MIMAT0003327
TargetScanVert: hsa-miR-449b-5p
TargetMiner: hsa-miR-449b-5p
miRDB: MIMAT0003327

Star sequence

Hsa-Mir-34-P3b_3p*

mirBase accession

MIMAT0009203

Sequence

39- CAGCCACAACUACCCUGCCAC -60

Get sequence

Proposed targets

microrna.org: MIMAT0009203
TargetScanVert: hsa-miR-449b-3p
TargetMiner: hsa-miR-449b-3p
miRDB: MIMAT0009203