Mir-34-P1

MirGeneDB ID

Hsa-Mir-34-P1

Family name

MIR-34 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-34a

Paralogues

Hsa-Mir-34-P2a Hsa-Mir-34-P2b Hsa-Mir-34-P3a-v1 Hsa-Mir-34-P3b Hsa-Mir-34-P3c

Orthologues

Aae-Mir-34 Aca-Mir-34-P1 Aga-Mir-34 Agr-Mir-34 Ami-Mir-34-P1 Asu-Mir-34 Bge-Mir-34 Bta-Mir-34-P1 Cbr-Mir-34 Cel-Mir-34 Cfa-Mir-34-P1 Cin-Mir-34 Cja-Mir-34-P1 Cli-Mir-34-P1 Cmi-Mir-34-P1 Cpi-Mir-34-P1 Cpo-Mir-34-P1 Cte-Mir-34 Dan-Mir-34 Dlo-Mir-34 Dma-Mir-34 Dme-Mir-34 Dmo-Mir-34 Dno-Mir-34-P1 Dpu-Mir-34 Dre-Mir-34-P1 Dsi-Mir-34 Dya-Mir-34 Ebu-Mir-34-P1 Eca-Mir-34-P1 Efe-Mir-34 Esc-Mir-34 Ete-Mir-34-P1 Gga-Mir-34-P1 Gja-Mir-34-P1 Gmo-Mir-34-P1 Gpa-Mir-34 Gsp-Mir-34 Hmi-Mir-34 Hru-Mir-34 Isc-Mir-34 Laf-Mir-34-P1 Lch-Mir-34-P1 Lgi-Mir-34 Lhy-Mir-34 Llo-Mir-34 Loc-Mir-34-P1 Mal-Mir-34-P1 Mdo-Mir-34-P1 Mgi-Mir-34 Mml-Mir-34-P1 Mmr-Mir-34-P1 Mmu-Mir-34-P1 Mom-Mir-34 Mun-Mir-34-P1 Neu-Mir-34-P1 Npo-Mir-34 Oan-Mir-34-P1 Obi-Mir-34 Ocu-Mir-34-P1 Ofu-Mir-34 Ovu-Mir-34 Pab-Mir-34-P1 Pau-Mir-34 Pbv-Mir-34-P1 Pca-Mir-34 Pdu-Mir-34 Pfl-Mir-34 Pma-Mir-34-P1 Pmi-Mir-34 Pve-Mir-34 Rno-Mir-34-P1 Rph-Mir-34 Sha-Mir-34-P1 Sko-Mir-34 Snu-Mir-34 Spt-Mir-34-P1 Spu-Mir-34 Sto-Mir-34-P1 Tca-Mir-34 Tgu-Mir-34-P1 Tni-Mir-34-P1 Tur-Mir-34 War-Mir-34 Xla-Mir-34-P1a Xla-Mir-34-P1b Xtr-Mir-34-P1

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr1: 9151692-9151756 [-] UCSC Ensembl

Seed

GGCAGUG

Precursor
(pre-Mir +30nt flank)

CCGUGGACCGGCCAGCUGUGAGUGUUUCUUUGGCAGUGUCUUAGCUGGUUGUUGUGAGCAAUAGUAAGGAAGCAAUCAGCAAGUAUACUGCCCUAGAAGUGCUGCACGUUGUGGGGCCCAAGAGG

Get precursor sequence

Structure

        10         20         30         40        50        60  
CCGUGGACCGGCCAGCU-   -  UG     UU        -|  A          GUGAGCAA 
                  GUG AG  UUUCU  GGCAGUGU CUU GCUGGUUGUU        \
                  CAC UC  GAAGA  CCGUCAUA GAA CGACUAACGA        U
GGAGAACCCGGGGUGUUG   G  GU     UC        U^  -          AGGAAUGA 
   120       110       100        90         80        70

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut -1 on both arms.

3' NTU

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-34-P1_5p

mirBase accession

MIMAT0000255

Sequence

0- UGGCAGUGUCUUAGCUGGUUGUU -23

Get sequence

Proposed targets

microrna.org: MIMAT0000255
TargetScanVert: hsa-miR-34a-5p
TargetMiner: hsa-miR-34a-5p
miRDB: MIMAT0000255

Star sequence

Hsa-Mir-34-P1_3p*

mirBase accession

MIMAT0004557

Sequence

42- CAAUCAGCAAGUAUACUGCCCUA -65

Get sequence

Proposed targets

microrna.org: MIMAT0004557
TargetScanVert: hsa-miR-34a-3p
TargetMiner: hsa-miR-34a-3p
miRDB: MIMAT0004557