MirGeneDB 3.0
MirGeneDB ID

Hsa-Mir-34-P3a

Family name MIR-34 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-mir-449c
Paralogues Hsa-Mir-34-P1  Hsa-Mir-34-P2a  Hsa-Mir-34-P2b  Hsa-Mir-34-P3b  Hsa-Mir-34-P3c 
Orthologues Aae-Mir-34  Aca-Mir-34-P3a  Aga-Mir-34  Agr-Mir-34  Ami-Mir-34-P3a  Asu-Mir-34  Bge-Mir-34  Bta-Mir-34-P3a  Cbr-Mir-34  Cel-Mir-34  Cin-Mir-34  Cja-Mir-34-P3a-v1  Cli-Mir-34-P3a  Cmi-Mir-34-P3a  Cpi-Mir-34-P3a  Cpo-Mir-34-P3a  Cte-Mir-34  Dan-Mir-34  Dlo-Mir-34  Dma-Mir-34  Dme-Mir-34  Dmo-Mir-34  Dno-Mir-34-P3a  Dpu-Mir-34  Dsi-Mir-34  Dya-Mir-34  Efe-Mir-34  Esc-Mir-34  Gga-Mir-34-P3a  Gja-Mir-34-P3a  Gpa-Mir-34  Gsp-Mir-34  Hmi-Mir-34  Hru-Mir-34  Isc-Mir-34  Lch-Mir-34-P3a  Lgi-Mir-34  Lhy-Mir-34  Llo-Mir-34  Loc-Mir-34-P3a  Mgi-Mir-34  Mmu-Mir-34-P3a  Mom-Mir-34  Mun-Mir-34-P3a  Npo-Mir-34  Oan-Mir-34-P3a  Obi-Mir-34  Ocu-Mir-34-P3a  Ofu-Mir-34  Ovu-Mir-34  Pab-Mir-34-P3a  Pau-Mir-34  Pbv-Mir-34-P3a  Pca-Mir-34  Pdu-Mir-34  Pfl-Mir-34  Pma-Mir-34-P3  Pmi-Mir-34  Pve-Mir-34  Rno-Mir-34-P3a  Rph-Mir-34  Sko-Mir-34  Snu-Mir-34  Spu-Mir-34  Sto-Mir-34-P3a  Tca-Mir-34  Tgu-Mir-34-P3a  Tur-Mir-34  War-Mir-34  Xla-Mir-34-P3a1  Xla-Mir-34-P3a2  Xtr-Mir-34-P3a 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chr5: 55172279-55172336 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-34-P3a-v1)		 Mir-34-P3c chr5: 55170546-55170607 [-] UCSC Ensembl
Mir-34-P3b chr5: 55170668-55170727 [-] UCSC Ensembl
Mir-34-P3a-v2 chr5: 55172278-55172337 [-] UCSC Ensembl
Mir-34-P3a-v1 chr5: 55172279-55172336 [-] UCSC Ensembl
Variant

Hsa-Mir-34-P3a-v1
Seed GGCAGUG
Precursor
(pre-Mir +30nt flank)		 
AGCAAAGGAUAAAGCUGGGAUGUGUCAGGUAGGCAGUGUAUUGCUAGCGGCUGUUAAUGAUUUUAACAGUUGCUAGUUGCACUCCUCUCUGUUGCAUUCAGAAGCACGCCCCCCAAAG
Get precursor sequence
Structure
        10          20        30        40        50          
AGCAAAGGAUAAAGCUG--|      U   GU   C      UU             AAUG 
                   GGAUGUG CAG  AGG AGUGUA  GCUAGCGGCUGUU    \
                   CUUACGU GUC  UCC UCACGU  UGAUCGUUGACAA    A
GAAACCCCCCGCACGAAGA^      U   UC   -      --             UUUU 
      110       100        90         80          70
Deep sequencing
Go to detailed chart
3' NTU No
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-34-P3a-v1_5p
mirBase accessionMIMAT0010251
Sequence 
0- AGGCAGUGUAUUGCUAGCGGCUGUU -25
Get sequence
Proposed targets microrna.org: MIMAT0010251
TargetScanVert: hsa-miR-449c-5p
TargetMiner: hsa-miR-449c-5p
miRDB: MIMAT0010251
Star sequence

Hsa-Mir-34-P3a-v1_3p*
mirBase accessionMIMAT0013771
Sequence 
36- CAGUUGCUAGUUGCACUCCUCU -58
Get sequence
Proposed targets microrna.org: MIMAT0013771
TargetScanVert: hsa-miR-449c-3p
TargetMiner: hsa-miR-449c-3p
miRDB: MIMAT0013771
Variant

Hsa-Mir-34-P3a-v2
Seed AGGCAGU
Precursor
(pre-Mir +30nt flank)		 
CAGCAAAGGAUAAAGCUGGGAUGUGUCAGGUAGGCAGUGUAUUGCUAGCGGCUGUUAAUGAUUUUAACAGUUGCUAGUUGCACUCCUCUCUGUUGCAUUCAGAAGCACGCCCCCCAAAGA
Get precursor sequence
Structure
        10          20        30        40        50        60 
CAGCAAAGGAUAAAGCUG--|      U   GU   C      UU             AAUG 
                    GGAUGUG CAG  AGG AGUGUA  GCUAGCGGCUGUU    \
                    CUUACGU GUC  UCC UCACGU  UGAUCGUUGACAA    A
AGAAACCCCCCGCACGAAGA^      U   UC   -      --             UUUU 
.       110       100        90         80          70
Deep sequencing
Go to detailed chart
3' NTU Unknown
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Mir-34-P3a-v2_5p
mirBase accessionMIMAT0010251
Sequence 
0- UAGGCAGUGUAUUGCUAGCGGCUGUU -26
Get sequence
Proposed targets microrna.org: MIMAT0010251
TargetScanVert: hsa-miR-449c-5p
TargetMiner: hsa-miR-449c-5p
miRDB: MIMAT0010251
Star sequence

Hsa-Mir-34-P3a-v2_3p*
mirBase accessionMIMAT0013771
Sequence 
37- CAGUUGCUAGUUGCACUCCUCUC -60
Get sequence
Proposed targets microrna.org: MIMAT0013771
TargetScanVert: hsa-miR-449c-3p
TargetMiner: hsa-miR-449c-3p
miRDB: MIMAT0013771