Mir-34-P3c

MirGeneDB ID

Hsa-Mir-34-P3c

Family name

MIR-34 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-449a

Paralogues

Hsa-Mir-34-P1 Hsa-Mir-34-P2a Hsa-Mir-34-P2b Hsa-Mir-34-P3a-v1 Hsa-Mir-34-P3b

Orthologues

Aae-Mir-34 Aca-Mir-34-P3c Aga-Mir-34 Agr-Mir-34 Ami-Mir-34-P3c Asu-Mir-34 Bge-Mir-34 Bta-Mir-34-P3c Cbr-Mir-34 Cel-Mir-34 Cfa-Mir-34-P3c Cin-Mir-34 Cja-Mir-34-P3c Cli-Mir-34-P3c Cmi-Mir-34-P3c Cpi-Mir-34-P3c Cpo-Mir-34-P3c Cte-Mir-34 Dan-Mir-34 Dlo-Mir-34 Dma-Mir-34 Dme-Mir-34 Dmo-Mir-34 Dno-Mir-34-P3c Dpu-Mir-34 Dsi-Mir-34 Dya-Mir-34 Eca-Mir-34-P3c Efe-Mir-34 Esc-Mir-34 Ete-Mir-34-P3c Gga-Mir-34-P3c Gja-Mir-34-P3c Gmo-Mir-34-P3c Gpa-Mir-34 Gsp-Mir-34 Hmi-Mir-34 Hru-Mir-34 Isc-Mir-34 Laf-Mir-34-P3c Lgi-Mir-34 Lhy-Mir-34 Llo-Mir-34 Loc-Mir-34-P3c Mal-Mir-34-P3c Mdo-Mir-34-P3c Mgi-Mir-34 Mml-Mir-34-P3c Mmr-Mir-34-P3c Mmu-Mir-34-P3c Mom-Mir-34 Neu-Mir-34-P3c Npo-Mir-34 Oan-Mir-34-P3c Obi-Mir-34 Ocu-Mir-34-P3c Ofu-Mir-34 Ovu-Mir-34 Pab-Mir-34-P3c Pau-Mir-34 Pbv-Mir-34-P3c Pca-Mir-34 Pdu-Mir-34 Pfl-Mir-34 Pma-Mir-34-P3 Pmi-Mir-34 Pve-Mir-34 Rno-Mir-34-P3c Rph-Mir-34 Sha-Mir-34-P3c Sko-Mir-34 Snu-Mir-34 Spt-Mir-34-P3c Spu-Mir-34 Sto-Mir-34-P3c Tca-Mir-34 Tgu-Mir-34-P3c Tni-Mir-34-P3c Tur-Mir-34 War-Mir-34 Xla-Mir-34-P3c1 Xla-Mir-34-P3c2 Xtr-Mir-34-P3c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr5: 55170546-55170607 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-34-P3c)

Mir-34-P3c chr5: 55170546-55170607 [-] UCSC Ensembl
Mir-34-P3b chr5: 55170668-55170727 [-] UCSC Ensembl
Mir-34-P3a-v2 chr5: 55172278-55172337 [-] UCSC Ensembl
Mir-34-P3a-v1 chr5: 55172279-55172336 [-] UCSC Ensembl

Seed

GGCAGUG

Precursor
(pre-Mir +30nt flank)

AAGUGCUCUGGAUACCUGUGUGUGAUGAGCUGGCAGUGUAUUGUUAGCUGGUUGAAUAUGUGAAUGGCAUCGGCUAACAUGCAACUGCUGUCUUAUUGCAUAUACAAUGAACAUCAGAGUGU

Get precursor sequence

Structure

        10          20        30         40        50        60
AAGUGCUCUGGAUACCU--     UG     C      -|    U          UGAAUAU 
                   GUGUG  AUGAG UGGCAG UGUAU GUUAGCUGGU       G
                   UAUAC  UAUUC GUCGUC ACGUA CAAUCGGCUA       U
UGUGAGACUACAAGUAACA     GU     U      A^    -          CGGUAAG 
120       110       100        90        80         70

Deep sequencing

Go to detailed chart

Comment

There is a second Dicer cut +1 on the 3p arm.

3' NTU

Motifs

UG at 5p(-14)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-34-P3c_5p

mirBase accession

MIMAT0001541

Sequence

0- UGGCAGUGUAUUGUUAGCUGGU -22

Get sequence

Proposed targets

microrna.org: MIMAT0001541
TargetScanVert: hsa-miR-449a
TargetMiner: hsa-miR-449a
miRDB: MIMAT0001541

Star sequence

Hsa-Mir-34-P3c_3p*

mirBase accession

None

Sequence

40- CGGCUAACAUGCAACUGCUGUC -62

Get sequence