MirGeneDB 3.0
MirGeneDB ID

Hsa-Let-7-P1b

Family name LET-7 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-let-7e
Paralogues Hsa-Let-7-P1c  Hsa-Let-7-P1d  Hsa-Let-7-P2a1  Hsa-Let-7-P2a2  Hsa-Let-7-P2a3  Hsa-Let-7-P2b1  Hsa-Let-7-P2b2  Hsa-Let-7-P2b3  Hsa-Let-7-P2c1  Hsa-Let-7-P2c2  Hsa-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P1b  Aga-Let-7  Agr-Let-7  Ami-Let-7-P1b  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P1b  Cfa-Let-7-P1b  Cin-Let-7-P1  Cja-Let-7-P1b  Cpi-Let-7-P1b  Cpo-Let-7-P1b  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dpu-Let-7  Dre-Let-7-P1b1  Dre-Let-7-P1b2  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P1b  Egr-Let-7  Esc-Let-7  Ete-Let-7-P1b  Gja-Let-7-P1b  Gmo-Let-7-P1b1  Gmo-Let-7-P1b2  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Laf-Let-7-P1b  Lan-Let-7  Lch-Let-7-P1b  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P1b  Mal-Let-7-P1b1  Mal-Let-7-P1b2  Mdo-Let-7-P1b  Mgi-Let-7  Mml-Let-7-P1b  Mmr-Let-7-P1b  Mmu-Let-7-P1b  Mom-Let-7  Mun-Let-7-P1b  Npo-Let-7  Oan-Let-7-P1b  Obi-Let-7  Ocu-Let-7-P1b  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P1b  Pau-Let-7  Pbv-Let-7-P1b  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P1b  Rph-Let-7  Sha-Let-7-P1b  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P1b  Spu-Let-7  Sro-Let-7  Sto-Let-7-P1b  Tca-Let-7  Tni-Let-7-P1b1  Tni-Let-7-P1b2  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P1b3  Xla-Let-7-P1b4  Xtr-Let-7-P1b 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chr19: 51692793-51692859 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P1b)		 Mir-10-P2b chr19: 51692618-51692677 [+] UCSC Ensembl
Let-7-P1b chr19: 51692793-51692859 [+] UCSC Ensembl
Mir-10-P3b chr19: 51693268-51693327 [+] UCSC Ensembl
Seed GAGGUAG
Precursor
(pre-Mir +30nt flank)		 
GGGUCUGUCCACCUGCCGCGCCCCCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAGGACACCCAAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGGCUGCGCCCUGCACGGGACGGGGCCC
Get precursor sequence
Structure
        10          20        30        40        50        60   
GGGUCUGUCCACCUGCC--|   CC  C   CU   G                UGAGGAGGACA 
                   GCGC  CC GGG  GAG UAGGAGGUUGUAUAGU           \
                   CGCG  GG CCC  UUC AUCCUCCGGCAUAUCA           C
CCCGGGGCAGGGCACGUCC^   UC  A   CU   G                CUAGAGGAACC 
     120       110       100        90        80        70
Deep sequencing
Go to detailed chart
3' NTU No
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Let-7-P1b_5p
mirBase accessionMIMAT0000066
Sequence 
0- UGAGGUAGGAGGUUGUAUAGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000066
TargetScanVert: hsa-let-7e-5p
TargetMiner: hsa-let-7e-5p
miRDB: MIMAT0000066
Star sequence

Hsa-Let-7-P1b_3p*
mirBase accessionMIMAT0004485
Sequence 
45- CUAUACGGCCUCCUAGCUUUCC -67
Get sequence
Proposed targets microrna.org: MIMAT0004485
TargetScanVert: hsa-let-7e-3p
TargetMiner: hsa-let-7e-3p
miRDB: MIMAT0004485