Let-7-P1d

MirGeneDB ID

Hsa-Let-7-P1d

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

Human (Homo sapiens)

MiRBase ID

hsa-let-7a-2

Paralogues

Hsa-Let-7-P1b Hsa-Let-7-P1c Hsa-Let-7-P2a1 Hsa-Let-7-P2a2 Hsa-Let-7-P2a3 Hsa-Let-7-P2b1 Hsa-Let-7-P2b2 Hsa-Let-7-P2b3 Hsa-Let-7-P2c1 Hsa-Let-7-P2c2 Hsa-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1d Ami-Let-7-P1d Bge-Let-7 Bpl-Let-7 Bta-Let-7-P1d Cfa-Let-7-P1d Cgi-Let-7 Cin-Let-7-P1 Cli-Let-7-P1d Cmi-Let-7-P1d Cpi-Let-7-P1d Cpo-Let-7-P1d Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P1d Dpu-Let-7 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P1d Gga-Let-7-P1d Gja-Let-7-P1d Gmo-Let-7-P1d1 Gmo-Let-7-P1d2 Hme-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P1d Lgi-Let-7 Loc-Let-7-P1d Mal-Let-7-P1d1 Mal-Let-7-P1d2 Mdo-Let-7-P1d Mml-Let-7-P1d Mmu-Let-7-P1d Mun-Let-7-P1d Npo-Let-7 Oan-Let-7-P1d Obi-Let-7 Ocu-Let-7-P1d Ovu-Let-7 Pbv-Let-7-P1d Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P1d Sha-Let-7-P1d Sko-Let-7 Spt-Let-7-P1d Spu-Let-7 Sto-Let-7-P1d Tca-Let-7 Tgu-Let-7-P1d Tni-Let-7-P1d1 Tni-Let-7-P1d2 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(hg38)

chr11: 122146523-122146589 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1d)

Mir-10-P3d chr11: 122099769-122099830 [-] UCSC Ensembl
Let-7-P1d chr11: 122146523-122146589 [-] UCSC Ensembl
Mir-10-P2d chr11: 122152240-122152296 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UCCAGCCAUUGUGACUGCAUGCUCCCAGGUUGAGGUAGUAGGUUGUAUAGUUUAGAAUUACAUCAAGGGAGAUAACUGUACAGCCUCCUAGCUUUCCUUGGGUCUUGCACUAAACAACAUGGUGAGA

Get precursor sequence

Structure

        10        20           30        40        50        60   
UCCAGCCAUUGUGACUGCA   U---|     UU   G   U             UAGAAUUACA 
                   UGC    CCCAGG  GAG UAG AGGUUGUAUAGUU          \
                   ACG    GGGUUC  UUC AUC UCCGACAUGUCAA          U
AGAGUGGUACAACAAAUC-   UUCU^     CU   G   C             UAGAGGGAAC 
     120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Ar	Bl	Bo	Bo	Bo	Bo	Bo	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Br	Es	Ga	He	He	He	He	He	Ki	Li	Lu	Ly	Mu	Ne	Pa	Pl	Pl	Sk	Sp	Sp	St	Su	Te	Th	To	Tr	Ve

Mature sequence

Hsa-Let-7-P1d_5p

mirBase accession

MIMAT0000062

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000062
TargetScanVert: hsa-let-7a-5p
TargetMiner: hsa-let-7a-5p
miRDB: MIMAT0000062

Star sequence

Hsa-Let-7-P1d_3p*

mirBase accession

MIMAT0010195

Sequence

45- CUGUACAGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

microrna.org: MIMAT0010195
TargetScanVert: hsa-let-7a-2-3p
TargetMiner: hsa-let-7a-2-3p
miRDB: MIMAT0010195