Let-7-P1d

MirGeneDB ID

Rno-Let-7-P1d

Family name

LET-7 (all species)

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7a-2

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P2a1 Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2 Rno-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1d Aga-Let-7 Agr-Let-7 Ami-Let-7-P1d Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P1d Cfa-Let-7-P1d Cin-Let-7-P1 Cja-Let-7-P1d Cli-Let-7-P1d Cmi-Let-7-P1d Cpi-Let-7-P1d Cpo-Let-7-P1d Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P1d Dpu-Let-7 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P1d Egr-Let-7 Esc-Let-7 Ete-Let-7-P1d Gga-Let-7-P1d Gja-Let-7-P1d Gmo-Let-7-P1d1 Gmo-Let-7-P1d2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1d Isc-Let-7 Laf-Let-7-P1d Lan-Let-7 Lch-Let-7-P1d Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1d Mal-Let-7-P1d1 Mal-Let-7-P1d2 Mdo-Let-7-P1d Mgi-Let-7 Mml-Let-7-P1d Mmr-Let-7-P1d Mmu-Let-7-P1d Mom-Let-7 Mun-Let-7-P1d Neu-Let-7-P1d Npo-Let-7 Oan-Let-7-P1d Obi-Let-7 Ocu-Let-7-P1d Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1d Pau-Let-7 Pbv-Let-7-P1d Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sha-Let-7-P1d Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1d Spu-Let-7 Sro-Let-7 Sto-Let-7-P1d Tca-Let-7 Tgu-Let-7-P1d Tni-Let-7-P1d1 Tni-Let-7-P1d2 Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr8: 45753280-45753346 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1d)

Mir-10-P2d chr8: 45746960-45747016 [+] UCSC Ensembl
Let-7-P1d chr8: 45753280-45753346 [+] UCSC Ensembl
Mir-10-P3d chr8: 45798274-45798335 [+] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UCCAGCCACUGUGACGGCAUGCUCCCAGGCUGAGGUAGUAGGUUGUAUAGUUUAGAGUUACAACAAGGGAGAUAACUGUACAGCCUCCUAGCUUUCCUUGGGACUUGCACAAAGCAACAUGGUGAGA

Get precursor sequence

Structure

        10        20           30        40        50        60   
UCCAGCCACUGUGACGGCA   ---|      CU   G   U             UAGAGUUACA 
                   UGC   UCCCAGG  GAG UAG AGGUUGUAUAGUU          \
                   ACG   AGGGUUC  UUC AUC UCCGACAUGUCAA          A
AGAGUGGUACAACGAAAC-   UUC^      CU   G   C             UAGAGGGAAC 
     120       110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P1d_5p

mirBase accession

MIMAT0000774

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000774
TargetScanVert: rno-let-7a-5p
miRDB: MIMAT0000774

Star sequence

Rno-Let-7-P1d_3p*

mirBase accession

MIMAT0017086

Sequence

45- CUGUACAGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

TargetScanVert: rno-let-7a-2-3p
miRDB: MIMAT0017086