Let-7-P2c3

MirGeneDB ID

Rno-Let-7-P2c3

Family name

LET-7 (all species)

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-let-7g

Paralogues

Rno-Let-7-P1b Rno-Let-7-P1c Rno-Let-7-P1d Rno-Let-7-P2a1 Rno-Let-7-P2a2 Rno-Let-7-P2a3 Rno-Let-7-P2b1 Rno-Let-7-P2b2 Rno-Let-7-P2b3 Rno-Let-7-P2c1 Rno-Let-7-P2c2

Orthologues

Aae-Let-7 Aca-Let-7-P2c3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2c3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2c3 Cfa-Let-7-P2c3 Cja-Let-7-P2c3 Cli-Let-7-P2c3 Cmi-Let-7-P2c3 Cpi-Let-7-P2c3 Cpo-Let-7-P2c3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2c3 Dpu-Let-7 Dre-Let-7-P2c3 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2c3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2c3 Gga-Let-7-P2c3 Gja-Let-7-P2c3 Gmo-Let-7-P2c3 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2c3 Isc-Let-7 Laf-Let-7-P2c3 Lan-Let-7 Lch-Let-7-P2c3 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2c3 Mal-Let-7-P2c3 Mdo-Let-7-P2c3 Mgi-Let-7 Mml-Let-7-P2c3 Mmr-Let-7-P2c3 Mmu-Let-7-P2c3 Mom-Let-7 Mun-Let-7-P2c3 Npo-Let-7 Oan-Let-7-P2c3 Obi-Let-7 Ocu-Let-7-P2c3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2c3 Pau-Let-7 Pbv-Let-7-P2c3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sha-Let-7-P2c3 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2c3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2c3 Tca-Let-7 Tgu-Let-7-P2c3 Tni-Let-7-P2c3 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2c3c Xla-Let-7-P2c3d Xtr-Let-7-P2c3

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(rn6)

chr8: 114874463-114874540 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2c3)

Mir-135-P1 chr8: 114847396-114847455 [+] UCSC Ensembl
Let-7-P2c3 chr8: 114874463-114874540 [+] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UGCUCCGUUCUCUUUUGCCUGAUUCCAGGCUGAGGUAGUAGUUUGUACAGUUUGAGGGUCUAUGAUACCACCCGGUACAGGAGAUAACUGUACAGGCCACUGCCUUGCCAGGAACAGCGCACCAGCUACCAAAUGUGG

Get precursor sequence

Structure

        10           20        30        40        50        60         
UGCUCCGUUCUCUUUUGC---|  A    A   U        A            UGAGGGUCUAUGAUAC 
                     CUG UUCC GGC GAGGUAGU GUUUGUACAGUU                \
                     GAC AAGG CCG UUCCGUCA CGGACAUGUCAA                C
GGUGUAAACCAUCGACCACGC^  -    A   -        C            UAGAGGACAUGGCCCA 
      130       120        110        100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

CNNC at 3p(+17)

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Let-7-P2c3_5p

mirBase accession

MIMAT0035719

Sequence

0- UGAGGUAGUAGUUUGUACAGUU -22

Get sequence

Proposed targets

TargetScanVert: rno-let-7g-5p
miRDB: MIMAT0035719

Star sequence

Rno-Let-7-P2c3_3p*

mirBase accession

MIMAT0035720

Sequence

57- CUGUACAGGCCACUGCCUUGC -78

Get sequence

Proposed targets

TargetScanVert: rno-let-7g-3p
miRDB: MIMAT0035720