MirGeneDB 3.0
MirGeneDB ID

Hsa-Let-7-P2a3

Family name LET-7 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-let-7f-2
Paralogues Hsa-Let-7-P1b  Hsa-Let-7-P1c  Hsa-Let-7-P1d  Hsa-Let-7-P2a1  Hsa-Let-7-P2a2  Hsa-Let-7-P2b1  Hsa-Let-7-P2b2  Hsa-Let-7-P2b3  Hsa-Let-7-P2c1  Hsa-Let-7-P2c2  Hsa-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2a3  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2a3  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2a3  Cfa-Let-7-P2a3  Cja-Let-7-P2a3  Cpi-Let-7-P2a3  Cpo-Let-7-P2a3  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2a3  Dpu-Let-7  Dre-Let-7-P2a3a  Dre-Let-7-P2a3b  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2a3  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2a3  Gja-Let-7-P2a3  Gmo-Let-7-P2a3a  Gmo-Let-7-P2a3b  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Laf-Let-7-P2a3  Lan-Let-7  Lch-Let-7-P2a3  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2a3  Mal-Let-7-P2a3a  Mal-Let-7-P2a3b  Mdo-Let-7-P2a3  Mgi-Let-7  Mml-Let-7-P2a3  Mmr-Let-7-P2a3  Mmu-Let-7-P2a3  Mom-Let-7  Mun-Let-7-P2a3  Neu-Let-7-P2a3  Npo-Let-7  Oan-Let-7-P2a3  Obi-Let-7  Ocu-Let-7-P2a3  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2a3  Pau-Let-7  Pbv-Let-7-P2a3  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P2a3  Rph-Let-7  Sha-Let-7-P2a3  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2a3  Spu-Let-7  Sro-Let-7  Sto-Let-7-P2a3  Tca-Let-7  Tgu-Let-7-P2a3  Tni-Let-7-P2a3a  Tni-Let-7-P2a3b  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P2a3d  Xtr-Let-7-P2a3 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chrX: 53557197-53557267 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2a3)		 Let-7-P2b3 chrX: 53556242-53556320 [-] UCSC Ensembl
Let-7-P2a3 chrX: 53557197-53557267 [-] UCSC Ensembl
Seed GAGGUAG
Precursor
(pre-Mir +30nt flank)		 
GCUGAAGAUGGACACUGGUGCUCUGUGGGAUGAGGUAGUAGAUUGUAUAGUUUUAGGGUCAUACCCCAUCUUGGAGAUAACUAUACAGUCUACUGUCUUUCCCACGGUGGUACACUUCUUCUCCGACUGGC
Get precursor sequence
Structure
        10         20         30        40        50        60     
GCUGAAGAUGGACACUG-     -|       U   GU                UUAGGGUCAUAC 
                  GUGCU CUGUGGGA GAG  AGUAGAUUGUAUAGUU            C
                  CAUGG GGCACCCU UUC  UCAUCUGACAUAUCAA            C
CGGUCAGCCUCUUCUUCA     U^       -   UG                UAGAGGUUCUAC 
 .       120       110       100         90        80        70
Deep sequencing
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3' NTU Yes
MotifsCNNC at 3p(+17)
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Let-7-P2a3_5p
mirBase accessionMIMAT0000067
Sequence 
0- UGAGGUAGUAGAUUGUAUAGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000067
TargetScanVert: hsa-let-7f-5p
TargetMiner: hsa-let-7f-5p
miRDB: MIMAT0000067
Star sequence

Hsa-Let-7-P2a3_3p*
mirBase accessionMIMAT0004487
Sequence 
50- CUAUACAGUCUACUGUCUUUC -71
Get sequence
Proposed targets microrna.org: MIMAT0004487
TargetScanVert: hsa-let-7f-2-3p
TargetMiner: hsa-let-7f-2-3p
miRDB: MIMAT0004487