MirGeneDB 3.0
MirGeneDB ID

Hsa-Let-7-P2b2

Family name LET-7 (all species)
Species Human (Homo sapiens)
MiRBase ID hsa-let-7b
Paralogues Hsa-Let-7-P1b  Hsa-Let-7-P1c  Hsa-Let-7-P1d  Hsa-Let-7-P2a1  Hsa-Let-7-P2a2  Hsa-Let-7-P2a3  Hsa-Let-7-P2b1  Hsa-Let-7-P2b3  Hsa-Let-7-P2c1  Hsa-Let-7-P2c2  Hsa-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2b2  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b2  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2b2  Cfa-Let-7-P2b2  Cja-Let-7-P2b2  Cli-Let-7-P2b2  Cmi-Let-7-P2b2  Cpi-Let-7-P2b2  Cpo-Let-7-P2b2  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2b2  Dpu-Let-7  Dre-Let-7-P2b2a  Dre-Let-7-P2b2b  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2b2  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2b2  Gga-Let-7-P2b2  Gja-Let-7-P2b2  Gmo-Let-7-P2b2a  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Laf-Let-7-P2b2  Lan-Let-7  Lch-Let-7-P2b2  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b2  Mal-Let-7-P2b2a  Mal-Let-7-P2b2b  Mdo-Let-7-P2b2  Mgi-Let-7  Mml-Let-7-P2b2  Mmr-Let-7-P2b2  Mmu-Let-7-P2b2  Mom-Let-7  Mun-Let-7-P2b2  Neu-Let-7-P2b2  Npo-Let-7  Oan-Let-7-P2b2  Obi-Let-7  Ocu-Let-7-P2b2  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2b2  Pau-Let-7  Pbv-Let-7-P2b2  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P2b2  Rph-Let-7  Sha-Let-7-P2b2  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b2  Spu-Let-7  Sro-Let-7  Sto-Let-7-P2b2  Tca-Let-7  Tgu-Let-7-P2b2  Tni-Let-7-P2b2a  Tni-Let-7-P2b2b  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P2b2c  Xla-Let-7-P2b2d  Xtr-Let-7-P2b2 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(hg38)		 chr22: 46113691-46113765 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2b2)		 Mir-3619 chr22: 46091059-46091112 [+] UCSC Ensembl
Let-7-P2a2 chr22: 46112752-46112820 [+] UCSC Ensembl
Let-7-P2b2 chr22: 46113691-46113765 [+] UCSC Ensembl
Seed GAGGUAG
Precursor
(pre-Mir +30nt flank)		 
UCCCGCAGUGCAAGGCCGGGCCUGGCGGGGUGAGGUAGUAGGUUGUGUGGUUUCAGGGCAGUGAUGUUGCCCCUCGGAAGAUAACUAUACAACCUACUGCCUUCCCUGAGGAGCCCAGUGACACGACCCCAUGGG
Get precursor sequence
Structure
        10          20         30        40        50        60       
UCCCGCAGUGCAAGGCC--    -| GG     U                     UCAGGGCAGUGAUG 
                   GGGC CU  CGGGG GAGGUAGUAGGUUGUGUGGUU              U
                   CCCG GG  GUCCC UUCCGUCAUCCAACAUAUCAA              U
GGGUACCCCAGCACAGUGA    A^ A-     -                     UAGAAGGCUCCCCG 
   130       120       110         100        90        80        70
Deep sequencing
Go to detailed chart
3' NTU Yes
MotifsNo
Tissue expression
- +
Dc Dc Dr Dr Xp Xp Bl Br Br Ce Ce Co Fo He Ki Le Li Li Lu Pa Pl Pl Sk Sk Sk Sm Sp Sp St Te Th Ut
Mature sequence

Hsa-Let-7-P2b2_5p
mirBase accessionMIMAT0000063
Sequence 
0- UGAGGUAGUAGGUUGUGUGGUU -22
Get sequence
Proposed targets microrna.org: MIMAT0000063
TargetScanVert: hsa-let-7b-5p
TargetMiner: hsa-let-7b-5p
miRDB: MIMAT0000063
Star sequence

Hsa-Let-7-P2b2_3p*
mirBase accessionMIMAT0004482
Sequence 
54- CUAUACAACCUACUGCCUUCC -75
Get sequence
Proposed targets microrna.org: MIMAT0004482
TargetScanVert: hsa-let-7b-3p
TargetMiner: hsa-let-7b-3p
miRDB: MIMAT0004482