Let-7-P1b

MirGeneDB ID

Mmu-Let-7-P1b

Family name

LET-7 (all species)

Seed

GAGGUAG

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7e

Paralogues

Mmu-Let-7-P1c Mmu-Let-7-P1d Mmu-Let-7-P2a1 Mmu-Let-7-P2a2 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b2 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1b Ami-Let-7-P1b Bge-Let-7 Bpl-Let-7 Bta-Let-7-P1b Cfa-Let-7-P1b Cgi-Let-7 Cin-Let-7-P1 Cpi-Let-7-P1b Cpo-Let-7-P1b Cte-Let-7 Dan-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dsi-Let-7 Dya-Let-7 Esc-Let-7 Ete-Let-7-P1b Gja-Let-7-P1b Gmo-Let-7-P1b1 Gmo-Let-7-P1b2 Hme-Let-7 Hsa-Let-7-P1b Isc-Let-7 Lan-Let-7 Lch-Let-7-P1b Lgi-Let-7 Loc-Let-7-P1b Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mdo-Let-7-P1b Mml-Let-7-P1b Mun-Let-7-P1b Npo-Let-7 Oan-Let-7-P1b Obi-Let-7 Ocu-Let-7-P1b Ovu-Let-7 Pbv-Let-7-P1b Pfl-Let-7 Pmi-Let-7 Rno-Let-7-P1b Sha-Let-7-P1b Sko-Let-7 Spt-Let-7-P1b Spu-Let-7 Sto-Let-7-P1b Tca-Let-7 Tni-Let-7-P1b1 Tni-Let-7-P1b2 Xbo-Let-7 Xla-Let-7-P1b3 Xla-Let-7-P1b4 Xtr-Let-7-P1b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr17: 17830366-17830432 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1b)

Mir-10-P2b chr17: 17830194-17830253 [+] UCSC Ensembl
Let-7-P1b chr17: 17830366-17830432 [+] UCSC Ensembl
Mir-10-P3b chr17: 17830817-17830876 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CAAUCUGCCCACCUGCCGCGCCCCCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAAGACACCCGAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGGCUGCGCCCUGCACUGGAAGGGGCCG

Get precursor sequence

Structure

        10          20        30        40        50        60   
CAAUCUGCCCACCUGCC--|   CC  C   CU   G                UGAGGAAGACA 
                   GCGC  CC GGG  GAG UAGGAGGUUGUAUAGU           \
                   CGCG  GG CCC  UUC AUCCUCCGGCAUAUCA           C
GCCGGGGAAGGUCACGUCC^   UC  A   CU   G                CUAGAGGAGCC 
     120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

Tissue expression

Bo	Br	Br	Ce	Em	Em	He	In	Ki	Li	Lu	Mu	Ov	Pa	Sk	Sp	Sp	Te

Mature sequence

Mmu-Let-7-P1b_5p

mirBase accession

MIMAT0000524

Sequence

0- UGAGGUAGGAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000524
TargetScanVert: mmu-let-7e-5p
miRDB: MIMAT0000524

Star sequence

Mmu-Let-7-P1b_3p*

mirBase accession

MIMAT0017016

Sequence

45- CUAUACGGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

TargetScanVert: mmu-let-7e-3p
miRDB: MIMAT0017016