Let-7-P1b

MirGeneDB ID

Mmu-Let-7-P1b

Family name

LET-7 (all species)

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7e

Paralogues

Mmu-Let-7-P1c Mmu-Let-7-P1d Mmu-Let-7-P2a1 Mmu-Let-7-P2a2 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b2 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P1b Aga-Let-7 Agr-Let-7 Ami-Let-7-P1b Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P1b Cfa-Let-7-P1b Cin-Let-7-P1 Cja-Let-7-P1b Cpi-Let-7-P1b Cpo-Let-7-P1b Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P1b Egr-Let-7 Esc-Let-7 Ete-Let-7-P1b Gja-Let-7-P1b Gmo-Let-7-P1b1 Gmo-Let-7-P1b2 Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P1b Isc-Let-7 Laf-Let-7-P1b Lan-Let-7 Lch-Let-7-P1b Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P1b Mal-Let-7-P1b1 Mal-Let-7-P1b2 Mdo-Let-7-P1b Mgi-Let-7 Mml-Let-7-P1b Mmr-Let-7-P1b Mom-Let-7 Mun-Let-7-P1b Npo-Let-7 Oan-Let-7-P1b Obi-Let-7 Ocu-Let-7-P1b Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P1b Pau-Let-7 Pbv-Let-7-P1b Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P1b Rph-Let-7 Sha-Let-7-P1b Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P1b Spu-Let-7 Sro-Let-7 Sto-Let-7-P1b Tca-Let-7 Tni-Let-7-P1b1 Tni-Let-7-P1b2 Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P1b3 Xla-Let-7-P1b4 Xtr-Let-7-P1b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr17: 17830366-17830432 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P1b)

Mir-10-P2b chr17: 17830194-17830253 [+] UCSC Ensembl
Let-7-P1b chr17: 17830366-17830432 [+] UCSC Ensembl
Mir-10-P3b chr17: 17830817-17830876 [+] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

CAAUCUGCCCACCUGCCGCGCCCCCCGGGCUGAGGUAGGAGGUUGUAUAGUUGAGGAAGACACCCGAGGAGAUCACUAUACGGCCUCCUAGCUUUCCCCAGGCUGCGCCCUGCACUGGAAGGGGCCG

Get precursor sequence

Structure

        10          20        30        40        50        60   
CAAUCUGCCCACCUGCC--|   CC  C   CU   G                UGAGGAAGACA 
                   GCGC  CC GGG  GAG UAGGAGGUUGUAUAGU           \
                   CGCG  GG CCC  UUC AUCCUCCGGCAUAUCA           C
GCCGGGGAAGGUCACGUCC^   UC  A   CU   G                CUAGAGGAGCC 
     120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Motifs

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Let-7-P1b_5p

mirBase accession

MIMAT0000524

Sequence

0- UGAGGUAGGAGGUUGUAUAGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000524
TargetScanVert: mmu-let-7e-5p
miRDB: MIMAT0000524

Star sequence

Mmu-Let-7-P1b_3p*

mirBase accession

MIMAT0017016

Sequence

45- CUAUACGGCCUCCUAGCUUUCC -67

Get sequence

Proposed targets

TargetScanVert: mmu-let-7e-3p
miRDB: MIMAT0017016