Let-7-P2a2

MirGeneDB ID

Mmu-Let-7-P2a2

Family name

LET-7 (all species)

Species

House mouse (Mus musculus)

MiRBase ID

mmu-let-7c-2

Paralogues

Mmu-Let-7-P1b Mmu-Let-7-P1c Mmu-Let-7-P1d Mmu-Let-7-P2a1 Mmu-Let-7-P2a3 Mmu-Let-7-P2b1 Mmu-Let-7-P2b2 Mmu-Let-7-P2b3 Mmu-Let-7-P2c1 Mmu-Let-7-P2c2 Mmu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a2 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a2 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2a2 Cfa-Let-7-P2a2 Cja-Let-7-P2a2 Cli-Let-7-P2a2 Cmi-Let-7-P2a2 Cpi-Let-7-P2a2 Cpo-Let-7-P2a2 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a2 Dpu-Let-7 Dre-Let-7-P2a2a Dre-Let-7-P2a2b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a2 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a2 Gga-Let-7-P2a2 Gja-Let-7-P2a2 Gmo-Let-7-P2a2a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a2 Isc-Let-7 Laf-Let-7-P2a2 Lan-Let-7 Lch-Let-7-P2a2 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a2 Mal-Let-7-P2a2a Mal-Let-7-P2a2b Mdo-Let-7-P2a2 Mgi-Let-7 Mml-Let-7-P2a2 Mmr-Let-7-P2a2 Mom-Let-7 Mun-Let-7-P2a2 Neu-Let-7-P2a2 Npo-Let-7 Oan-Let-7-P2a2 Obi-Let-7 Ocu-Let-7-P2a2 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a2 Pau-Let-7 Pbv-Let-7-P2a2 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2a2 Rph-Let-7 Sha-Let-7-P2a2 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a2 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a2 Tca-Let-7 Tgu-Let-7-P2a2 Tni-Let-7-P2a2a Tni-Let-7-P2a2b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a2c Xla-Let-7-P2a2d Xtr-Let-7-P2a2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(mm10)

chr15: 85706616-85706684 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a2)

Let-7-P2a2 chr15: 85706616-85706684 [+] UCSC Ensembl
Let-7-P2b2 chr15: 85707325-85707399 [+] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UACGCCAAGACUGACUGACGGCCUUUGGGGUGAGGUAGUAGGUUGUAUGGUUUUGGGCUCUGCCCCGCUCUGCGGUAACUAUACAAUCUACUGUCUUUCCUGAAGUGGCCGCAAUAUCUGCAGUGGAUA

Get precursor sequence

Structure

        10        20         30        40        50        60    
UACGCCAAGACUGACUGA     -|  G   U   GU                UUGGGCUCUGC 
                  CGGCC UUU GGG GAG  AGUAGGUUGUAUGGUU           C
                  GCCGG GAA UCC UUC  UCAUCUAACAUAUCAA           C
AUAGGUGACGUCUAUAAC     U^  G   U   UG                UGGCGUCUCGC 
       120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

Tissue expression

Br	Br	Ce	Ce	Em	Em	He	Ki	Li	Lu	Ov	Pa	Sk	Sp	Te

Mature sequence

Mmu-Let-7-P2a2_5p

mirBase accession

MIMAT0000523

Sequence

0- UGAGGUAGUAGGUUGUAUGGUU -22

Get sequence

Proposed targets

microrna.org: MIMAT0000523
TargetScanVert: mmu-let-7c-5p
miRDB: MIMAT0000523

Star sequence

Mmu-Let-7-P2a2_3p*

mirBase accession

MIMAT0005439

Sequence

48- CUAUACAAUCUACUGUCUUUC -69

Get sequence

Proposed targets

microrna.org: MIMAT0005439
TargetScanVert: mmu-let-7c-2-3p
miRDB: MIMAT0005439