Let-7-P2a2

MirGeneDB ID

Bta-Let-7-P2a2

Family name

LET-7 (all species)

Species

Cow (Bos taurus)

MiRBase ID

bta-let-7a-3

Paralogues

Bta-Let-7-P1b Bta-Let-7-P1c Bta-Let-7-P1d Bta-Let-7-P2a1 Bta-Let-7-P2a3 Bta-Let-7-P2b1 Bta-Let-7-P2b2 Bta-Let-7-P2b3 Bta-Let-7-P2c1 Bta-Let-7-P2c2 Bta-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a2 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a2 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cfa-Let-7-P2a2 Cja-Let-7-P2a2 Cli-Let-7-P2a2 Cmi-Let-7-P2a2 Cpi-Let-7-P2a2 Cpo-Let-7-P2a2 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2a2 Dpu-Let-7 Dre-Let-7-P2a2a Dre-Let-7-P2a2b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2a2 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2a2 Gga-Let-7-P2a2 Gja-Let-7-P2a2 Gmo-Let-7-P2a2a Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2a2 Isc-Let-7 Laf-Let-7-P2a2 Lan-Let-7 Lch-Let-7-P2a2 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a2 Mal-Let-7-P2a2a Mal-Let-7-P2a2b Mdo-Let-7-P2a2 Mgi-Let-7 Mml-Let-7-P2a2 Mmr-Let-7-P2a2 Mmu-Let-7-P2a2 Mom-Let-7 Mun-Let-7-P2a2 Neu-Let-7-P2a2 Npo-Let-7 Oan-Let-7-P2a2 Obi-Let-7 Ocu-Let-7-P2a2 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2a2 Pau-Let-7 Pbv-Let-7-P2a2 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2a2 Rph-Let-7 Sha-Let-7-P2a2 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a2 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2a2 Tca-Let-7 Tgu-Let-7-P2a2 Tni-Let-7-P2a2a Tni-Let-7-P2a2b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2a2c Xla-Let-7-P2a2d Xtr-Let-7-P2a2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037332.1: 116408413-116408481 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a2)

Let-7-P2a2 NC_037332.1: 116408413-116408481 [+] UCSC Ensembl
Let-7-P2b2 NC_037332.1: 116409215-116409290 [+] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

GCUCCGAGACUGACCGACGGCCCUUUGGGGUGAGGUAGUAGGUUGUAUAGUUUGGGGCUCUGCCCUGCUAUGGGAUAACUAUACAAUCUACUGUCUUUCCUGAAGUGGCUGUAAUACCGACAGCGGCCA

Get precursor sequence

Structure

        10         20         30        40        50        60    
GCUCCGAGACUGACCGA-     -|  UG   U   GU                UGGGGCUCUGC 
                  CGGCC CUU  GGG GAG  AGUAGGUUGUAUAGUU           C
                  GUCGG GAA  CCU UUC  UCAUCUAACAUAUCAA           C
ACCGGCGACAGCCAUAAU     U^  GU   -   UG                UAGGGUAUCGU 
       120       110       100         90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

Tissue expression

Ad	Bo	Br	Ce	Co	Co	De	Fe	He	Hy	Ir	Ki	La	Lo	Mi	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Let-7-P2a2_5p

mirBase accession

MIMAT0003844

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

TargetScanVert: bta-let-7a-5p

Star sequence

Bta-Let-7-P2a2_3p*

mirBase accession

MIMAT0004330

Sequence

48- CUAUACAAUCUACUGUCUUUC -69

Get sequence

Proposed targets

TargetScanVert: bta-let-7a-3p