Let-7-P2b3

MirGeneDB ID

Xtr-Let-7-P2b3

Family name

LET-7 (all species)

Species

Tropical clawed frog (Xenopus tropicalis)

MiRBase ID

xtr-mir-98

Paralogues

Xtr-Let-7-P1b Xtr-Let-7-P1c Xtr-Let-7-P2a1 Xtr-Let-7-P2a2 Xtr-Let-7-P2a3 Xtr-Let-7-P2b2 Xtr-Let-7-P2c2 Xtr-Let-7-P2c3 Xtr-Let-7-P2c4

Orthologues

Aae-Let-7 Aca-Let-7-P2b3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b3 Cfa-Let-7-P2b3 Cja-Let-7-P2b3 Cpi-Let-7-P2b3 Cpo-Let-7-P2b3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b3 Dpu-Let-7 Dre-Let-7-P2b3a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b3 Gja-Let-7-P2b3 Gmo-Let-7-P2b3a Gmo-Let-7-P2b3b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b3 Isc-Let-7 Laf-Let-7-P2b3 Lan-Let-7 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b3 Mal-Let-7-P2b3a Mgi-Let-7 Mml-Let-7-P2b3 Mmr-Let-7-P2b3 Mmu-Let-7-P2b3 Mom-Let-7 Mun-Let-7-P2b3 Npo-Let-7 Oan-Let-7-P2b3 Obi-Let-7 Ocu-Let-7-P2b3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b3 Pau-Let-7 Pbv-Let-7-P2b3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b3 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b3 Tca-Let-7 Tni-Let-7-P2b3a Tni-Let-7-P2b3b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b3c Xla-Let-7-P2b3d

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(xenTro9_add)

chr8: 8410567-8410643 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b3)

Let-7-P2b3 chr8: 8410567-8410643 [-] UCSC Ensembl
Let-7-P2a3 chr8: 8410824-8410894 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

CCUGCACUACACUCUCUGCCCUCUUCAGGAUGAGGUAGUAAGUUGUAUUGUUGUGGGGGUUUUUAUUUCCCCAAAUUAGGAGAUAACUAUACAGCUUACUGCCUUCCCUGCAGCAUGGUAAUUUAAUUCUCUGAUGU

Get precursor sequence

Structure

        10         20         30        40        50        60        
CCUGCACUACACUCUCU-   CU-| U    AU                 U   GUGGGGGUUUUUAUU 
                  GCC   CU CAGG  GAGGUAGUAAGUUGUAU GUU               U
                  UGG   GA GUCC  UUCCGUCAUUCGACAUA CAA               C
UGUAGUCUCUUAAUUUAA   UAC^ C    C-                 U   UAGAGGAUUAAACCC 
     130       120       110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

An	Br	Em	Em	He	Ve

Mature sequence

Xtr-Let-7-P2b3_5p

mirBase accession

MIMAT0003581

Sequence

0- UGAGGUAGUAAGUUGUAUUGUU -22

Get sequence

Proposed targets

TargetScanVert: xtr-miR-98

Star sequence

Xtr-Let-7-P2b3_3p*

mirBase accession

None

Sequence

56- CUAUACAGCUUACUGCCUUCC -77

Get sequence