MirGeneDB 3.0

MirGeneDB ID

Gja-Let-7-P2b3

Family name LET-7 (all species)
Species Schlegels Japanese gecko (Gekko japonicus)
MiRBase ID
Paralogues Gja-Let-7-P1b  Gja-Let-7-P1c  Gja-Let-7-P1d  Gja-Let-7-P2a1  Gja-Let-7-P2a2  Gja-Let-7-P2a3  Gja-Let-7-P2a4  Gja-Let-7-P2b1  Gja-Let-7-P2b2  Gja-Let-7-P2b4  Gja-Let-7-P2c1  Gja-Let-7-P2c2  Gja-Let-7-P2c3 
Orthologues Aae-Let-7  Aca-Let-7-P2b3  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b3  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Bta-Let-7-P2b3  Cfa-Let-7-P2b3  Cja-Let-7-P2b3  Cpi-Let-7-P2b3  Cpo-Let-7-P2b3  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dno-Let-7-P2b3  Dpu-Let-7  Dre-Let-7-P2b3a  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Eca-Let-7-P2b3  Egr-Let-7  Esc-Let-7  Ete-Let-7-P2b3  Gmo-Let-7-P2b3a  Gmo-Let-7-P2b3b  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Hsa-Let-7-P2b3  Isc-Let-7  Laf-Let-7-P2b3  Lan-Let-7  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b3  Mal-Let-7-P2b3a  Mgi-Let-7  Mml-Let-7-P2b3  Mmr-Let-7-P2b3  Mmu-Let-7-P2b3  Mom-Let-7  Mun-Let-7-P2b3  Npo-Let-7  Oan-Let-7-P2b3  Obi-Let-7  Ocu-Let-7-P2b3  Ofu-Let-7  Ovu-Let-7  Pab-Let-7-P2b3  Pau-Let-7  Pbv-Let-7-P2b3  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rno-Let-7-P2b3  Rph-Let-7  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b3  Spu-Let-7  Sro-Let-7  Sto-Let-7-P2b3  Tca-Let-7  Tni-Let-7-P2b3a  Tni-Let-7-P2b3b  Tur-Let-7  War-Let-7  Xbo-Let-7  Xla-Let-7-P2b3c  Xla-Let-7-P2b3d  Xtr-Let-7-P2b3 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(GCF_001447785.1_Gekko_japonicus)
NW_015173237.1: 128629-128706 [+]
Clustered miRNAs
(< 50kb from Let-7-P2b3)
Let-7-P2a3 NW_015173237.1: 127969-128039 [+]
Let-7-P2b3 NW_015173237.1: 128629-128706 [+]
Seed GAGGUAG
Precursor
(pre-Mir +30nt flank)
GGGGAGGUGUCUCCGUUGCUCCUGCUGAGGUGAGGUAGUAAGUUGUAUUGUUGUGGGGUAGGGAUUUGUGCCCCAAAUCAGAGAUAACUAUACAACUUACUACUUUCCCCAGCUGGGGUGAAGUGCCCAGGAUUUGGG
Get precursor sequence
Structure
        10          20        30        40        50        60         
GGGGAGGUGUCUCCGUU--|    U    A  UG                U   GUGGGGUAGGGAUUUG 
                   GCUCC GCUG GG  AGGUAGUAAGUUGUAU GUU                \
                   UGGGG CGAC CC  UUCAUCAUUCAACAUA CAA                U
GGGUUUAGGACCCGUGAAG^    U    -  CU                U   UAGAGACUAAACCCCG 
      130       120       110        100        90        80        70
Deep sequencing
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CommentThere is likely a 1 nt mismatch at position 11 on the 5p arm between the source of the genome (G. japonicus) and the source of the reads (C. variegatus) accounting for the paucity of reads of the mature miRNA.
3' NTU Yes
MotifsUG at 5p(-14), UGUG in loop
Tissue expression
- +
To
Mature sequence

Gja-Let-7-P2b3_5p

mirBase accessionNone
Sequence
0- UGAGGUAGUAAGUUGUAUUGUU -22
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Star sequence

Gja-Let-7-P2b3_3p*

mirBase accessionNone
Sequence
57- CUAUACAACUUACUACUUUCC -78
Get sequence