Let-7-P2b3

MirGeneDB ID

Ocu-Let-7-P2b3

Family name

LET-7 (all species)

Species

Rabbit (Oryctolagus cuniculus)

MiRBase ID

ocu-mir-98

Paralogues

Ocu-Let-7-P1b Ocu-Let-7-P1c Ocu-Let-7-P1d Ocu-Let-7-P2a1 Ocu-Let-7-P2a2 Ocu-Let-7-P2a3 Ocu-Let-7-P2b1 Ocu-Let-7-P2b2 Ocu-Let-7-P2c1 Ocu-Let-7-P2c2 Ocu-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b3 Cfa-Let-7-P2b3 Cja-Let-7-P2b3 Cpi-Let-7-P2b3 Cpo-Let-7-P2b3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b3 Dpu-Let-7 Dre-Let-7-P2b3a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b3 Gja-Let-7-P2b3 Gmo-Let-7-P2b3a Gmo-Let-7-P2b3b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b3 Isc-Let-7 Laf-Let-7-P2b3 Lan-Let-7 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b3 Mal-Let-7-P2b3a Mgi-Let-7 Mml-Let-7-P2b3 Mmr-Let-7-P2b3 Mmu-Let-7-P2b3 Mom-Let-7 Mun-Let-7-P2b3 Npo-Let-7 Oan-Let-7-P2b3 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b3 Pau-Let-7 Pbv-Let-7-P2b3 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b3 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b3 Tca-Let-7 Tni-Let-7-P2b3a Tni-Let-7-P2b3b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b3c Xla-Let-7-P2b3d Xtr-Let-7-P2b3

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(oryCun2_add)

chrX: 35039089-35039167 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b3)

Let-7-P2b3 chrX: 35039089-35039167 [-] UCSC Ensembl
Let-7-P2a3 chrX: 35040026-35040096 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

CCUUGCUGGAUGACUCUGCUCAUGCCGGGGUGAGGUAGUAAGUUGUAUUGUUGUGGGGUAGGGAUUUUAGGCCCCAAUAAGAAGAUAACUAUACAACUUACUACUUUCCCUGAUGUGUGGCAUGUUCACACUCUUGGCA

Get precursor sequence

Structure

        10         20         30        40        50        60         
CCUUGCUGGAUGACUCU-   -|  GC     U                 U   GUGGGGUAGGGAUUUU 
                  GCU CAU  CGGGG GAGGUAGUAAGUUGUAU GUU                A
                  CGG GUG  GUCCC UUUCAUCAUUCAACAUA CAA                G
ACGGUUCUCACACUUGUA   U^  UA     -                 U   UAGAAGAAUAACCCCG 
       130       120       110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

He	Ki	Te	To	Wh

Mature sequence

Ocu-Let-7-P2b3_5p

mirBase accession

MIMAT0048180

Sequence

0- UGAGGUAGUAAGUUGUAUUGUU -22

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Star sequence

Ocu-Let-7-P2b3_3p*

mirBase accession

MIMAT0048181

Sequence

58- CUAUACAACUUACUACUUUCC -79

Get sequence