Let-7-P2b3

MirGeneDB ID

Pbv-Let-7-P2b3

Family name

LET-7 (all species)

Species

Burmese python (Python bivittatus)

MiRBase ID

pbv-mir-98

Paralogues

Pbv-Let-7-P1b Pbv-Let-7-P1c Pbv-Let-7-P1d Pbv-Let-7-P2a1 Pbv-Let-7-P2a2 Pbv-Let-7-P2a3 Pbv-Let-7-P2a4 Pbv-Let-7-P2b1 Pbv-Let-7-P2b2 Pbv-Let-7-P2b4 Pbv-Let-7-P2c1 Pbv-Let-7-P2c2 Pbv-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b3 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b3 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Bta-Let-7-P2b3 Cfa-Let-7-P2b3 Cja-Let-7-P2b3 Cpi-Let-7-P2b3 Cpo-Let-7-P2b3 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dno-Let-7-P2b3 Dpu-Let-7 Dre-Let-7-P2b3a Dsi-Let-7 Dya-Let-7 Eba-Let-7 Eca-Let-7-P2b3 Egr-Let-7 Esc-Let-7 Ete-Let-7-P2b3 Gja-Let-7-P2b3 Gmo-Let-7-P2b3a Gmo-Let-7-P2b3b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Hsa-Let-7-P2b3 Isc-Let-7 Laf-Let-7-P2b3 Lan-Let-7 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b3 Mal-Let-7-P2b3a Mgi-Let-7 Mml-Let-7-P2b3 Mmr-Let-7-P2b3 Mmu-Let-7-P2b3 Mom-Let-7 Mun-Let-7-P2b3 Npo-Let-7 Oan-Let-7-P2b3 Obi-Let-7 Ocu-Let-7-P2b3 Ofu-Let-7 Ovu-Let-7 Pab-Let-7-P2b3 Pau-Let-7 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rno-Let-7-P2b3 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b3 Spu-Let-7 Sro-Let-7 Sto-Let-7-P2b3 Tca-Let-7 Tni-Let-7-P2b3a Tni-Let-7-P2b3b Tur-Let-7 War-Let-7 Xbo-Let-7 Xla-Let-7-P2b3c Xla-Let-7-P2b3d Xtr-Let-7-P2b3

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_000186305.2_Python_molurus_bivittatus)

KE954158.1: 74654-74731 [+]

Clustered miRNAs
(< 50kb from Let-7-P2b3)

Let-7-P2a3 KE954158.1: 74219-74289 [+]
Let-7-P2b3 KE954158.1: 74654-74731 [+]

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

AAGUGUUUGUGCAUCUUGCUCCUACCAGGGUGAGGUAGUAAGUUGUAUUGUUGUGGGGUAGGGAUUUGUGCCCCAAAUCAGAGAUAACUAUACAACUUACUACUUUCCCUGUGUGGGGUAAAGUACCCAAGAUUGUGU

Get precursor sequence

Structure

        10          20         30        40        50        60         
AAGUGUUUGUGCAUCUU--| U     -     U                 U   GUGGGGUAGGGAUUUG 
                   GC CCUAC CAGGG GAGGUAGUAAGUUGUAU GUU                \
                   UG GGGUG GUCCC UUUCAUCAUUCAACAUA CAA                U
UGUGUUAGAACCCAUGAAA^ -     U     -                 U   UAGAGACUAAACCCCG 
      130       120        110        100        90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

To

Mature sequence

Pbv-Let-7-P2b3_5p

mirBase accession

MIMAT0038893

Sequence

0- UGAGGUAGUAAGUUGUAUUGUU -22

Get sequence

Star sequence

Pbv-Let-7-P2b3_3p*

mirBase accession

MIMAT0038894

Sequence

57- CUAUACAACUUACUACUUUCC -78

Get sequence