Let-7-P2a4

MirGeneDB ID

Pbv-Let-7-P2a4

Family name

LET-7 (all species)

Species

Burmese python (Python bivittatus)

MiRBase ID

pbv-let-7e

Paralogues

Pbv-Let-7-P1b Pbv-Let-7-P1c Pbv-Let-7-P1d Pbv-Let-7-P2a1 Pbv-Let-7-P2a2 Pbv-Let-7-P2a3 Pbv-Let-7-P2b1 Pbv-Let-7-P2b2 Pbv-Let-7-P2b3 Pbv-Let-7-P2b4 Pbv-Let-7-P2c1 Pbv-Let-7-P2c2 Pbv-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2a4 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a4 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cli-Let-7-P2a4 Cmi-Let-7-P2a4 Cpi-Let-7-P2a4 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P2a4a Dre-Let-7-P2a4b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gga-Let-7-P2a4 Gja-Let-7-P2a4 Gmo-Let-7-P2a4a Gmo-Let-7-P2a4b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2a4 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a4 Mal-Let-7-P2a4a Mal-Let-7-P2a4b Mgi-Let-7 Mom-Let-7 Mun-Let-7-P2a4 Npo-Let-7 Oan-Let-7-P2a4 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a4 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2a4 Tni-Let-7-P2a4a Tni-Let-7-P2a4b Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_000186305.2_Python_molurus_bivittatus)

KE953223.1: 218880-218950 [+]

Clustered miRNAs
(< 50kb from Let-7-P2a4)

Let-7-P2a4 KE953223.1: 218880-218950 [+]
Let-7-P2b4 KE953223.1: 219107-219183 [+]

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UGACCAUCGAAACAAUGCUGUCCUUGAGGCUGAGGUAGUAGAUUGAAUAGUUGUGGAGCCAUCUUCUCCCUUUGAGCUAACUAUACAAUCUACUGUCUUUCCUAAGGAGGCAGUCAGUUCAUCUGCUCCUA

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Structure

        10         20         30        40        50        60     
UGACCAUCGAAACAAUG-     -|  G   CU   GU         A      GUGGAGCCAUCU 
                  CUGUC CUU AGG  GAG  AGUAGAUUG AUAGUU            U
                  GACGG GGA UCC  UUC  UCAUCUAAC UAUCAA            C
AUCCUCGUCUACUUGACU     A^  A   U-   UG         A      UCGAGUUUCCCU 
 .       120       110       100         90        80        70

Deep sequencing

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Comment

There are Dicer cuts -1 on both arms and -2 on the 3p arm.

3' NTU

Yes

Motifs

UGUG in loop

Tissue expression

To

Mature sequence

Pbv-Let-7-P2a4_5p

mirBase accession

MIMAT0038803

Sequence

0- UGAGGUAGUAGAUUGAAUAGUU -22

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Star sequence

Pbv-Let-7-P2a4_3p*

mirBase accession

MIMAT0038804

Sequence

50- CUAUACAAUCUACUGUCUUUC -71

Get sequence