Let-7-P2a4

MirGeneDB ID

Cmi-Let-7-P2a4

Family name

Species

Australian ghostshark (Callorhinchus milii)

MiRBase ID

Paralogues

Cmi-Let-7-P1d Cmi-Let-7-P2a1 Cmi-Let-7-P2a2 Cmi-Let-7-P2b2 Cmi-Let-7-P2b4 Cmi-Let-7-P2c1 Cmi-Let-7-P2c2 Cmi-Let-7-P2c3 Cmi-Let-7-P2c4

Orthologues

Aae-Let-7 Aca-Let-7-P2a4 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2a4 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cli-Let-7-P2a4 Cpi-Let-7-P2a4 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dre-Let-7-P2a4a Dre-Let-7-P2a4b Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gga-Let-7-P2a4 Gja-Let-7-P2a4 Gmo-Let-7-P2a4a Gmo-Let-7-P2a4b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2a4 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2a4 Mal-Let-7-P2a4a Mal-Let-7-P2a4b Mgi-Let-7 Mom-Let-7 Mun-Let-7-P2a4 Npo-Let-7 Oan-Let-7-P2a4 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pbv-Let-7-P2a4 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2a4 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2a4 Tni-Let-7-P2a4a Tni-Let-7-P2a4b Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Bilateria

Genome context
(GCA_000165045.2_Callorhinchus_milii-6.1.3)

KI636238.1: 143839-143909 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2a4)

Let-7-P2b4 KI636238.1: 142747-142824 [-] UCSC Ensembl
Let-7-P2a4 KI636238.1: 143839-143909 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UGAAGCUGGUGUCCCAGCUGUCCUUAGGGCUGAGGUAGUAGAUUGUAUAGUUGUGAGGUUGUACACCUCCUCUGAGAUAACUAUGCAAUCUACUGUCUUUCCUGAAGAGACAGAAAGAACUGGGGACGGGA

Get precursor sequence

Structure

        10         20         30        40        50        60     
UGAAGCUGGUGUCCCAG-     -|  A   CU   GU                GUGAGGUUGUAC 
                  CUGUC CUU GGG  GAG  AGUAGAUUGUAUAGUU            A
                  GACAG GAA UCC  UUC  UCAUCUAACGUAUCAA            C
AGGGCAGGGGUCAAGAAA     A^  G   U-   UG                UAGAGUCUCCUC 
 .       120       110       100         90        80        70

Deep sequencing

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3' NTU

Yes

Motifs

UGUG in loop

Tissue expression

Bl	Br	Ey	Gi	He	In	Ki	Li	Mu	Ov	Pa	Re	Sk	Sp	Te	Ut

Mature sequence

Cmi-Let-7-P2a4_5p

mirBase accession

None

Sequence

0- UGAGGUAGUAGAUUGUAUAGUU -22

Get sequence

Star sequence

Cmi-Let-7-P2a4_3p*

mirBase accession

None

Sequence

50- CUAUGCAAUCUACUGUCUUUC -71

Get sequence