Mir-430-P2

MirGeneDB ID

Hsa-Mir-430-P2

Family name

MIR-430 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-302c

Paralogues

Hsa-Mir-430-P1 Hsa-Mir-430-P3 Hsa-Mir-430-P4 Hsa-Mir-430-P5 Hsa-Mir-430-P6 Hsa-Mir-430-P7 Hsa-Mir-430-P8a Hsa-Mir-430-P8b Hsa-Mir-430-P9 Hsa-Mir-430-P10 Hsa-Mir-430-P11 Hsa-Mir-430-P12a Hsa-Mir-430-P12b Hsa-Mir-430-P13 Hsa-Mir-430-P14 Hsa-Mir-430-P15 Hsa-Mir-430-P16a Hsa-Mir-430-P16b Hsa-Mir-430-P17 Hsa-Mir-430-P18 Hsa-Mir-430-P19 Hsa-Mir-430-P20 Hsa-Mir-430-P21 Hsa-Mir-430-P22 Hsa-Mir-430-P23 Hsa-Mir-430-P24 Hsa-Mir-430-P25 Hsa-Mir-430-P26 Hsa-Mir-430-P27 Hsa-Mir-430-P28 Hsa-Mir-430-P29a Hsa-Mir-430-P29b Hsa-Mir-430-P29c Hsa-Mir-430-P30 Hsa-Mir-430-P31a Hsa-Mir-430-P31b Hsa-Mir-430-P32 Hsa-Mir-430-P33a Hsa-Mir-430-P33b Hsa-Mir-430-P34a Hsa-Mir-430-P34b Hsa-Mir-430-P35 Hsa-Mir-430-P36 Hsa-Mir-430-P37a Hsa-Mir-430-P37b Hsa-Mir-430-P37c Hsa-Mir-430-P38 Hsa-Mir-430-P39 Hsa-Mir-430-P40a Hsa-Mir-430-P40b Hsa-Mir-430-P41a Hsa-Mir-430-P41b

Orthologues

Ami-Mir-430-P2 Bta-Mir-430-P2 Cfa-Mir-430-P2 Cja-Mir-430-P2 Cli-Mir-430-P2 Cmi-Mir-430-P2 Cpi-Mir-430-P2 Cpo-Mir-430-P2 Dno-Mir-430-P2 Dre-Mir-430-o2a1 Dre-Mir-430-o2a2 Dre-Mir-430-o2a3 Dre-Mir-430-o2a4 Dre-Mir-430-o2a5 Dre-Mir-430-o2a6 Dre-Mir-430-o2a7 Dre-Mir-430-o2a8 Dre-Mir-430-o2a9 Dre-Mir-430-o2a10 Dre-Mir-430-o2a11 Dre-Mir-430-o2a12 Dre-Mir-430-o2a13 Dre-Mir-430-o2a14 Dre-Mir-430-o2b Dre-Mir-430-o2c1 Dre-Mir-430-o2c2 Dre-Mir-430-o2c3 Dre-Mir-430-o2d1 Dre-Mir-430-o2d2 Eca-Mir-430-P2 Ete-Mir-430-P2 Gga-Mir-430-P2 Laf-Mir-430-P2 Mdo-Mir-430-P2 Mml-Mir-430-P2 Mmr-Mir-430-P2 Mmu-Mir-430-P2 Neu-Mir-430-P2 Oan-Mir-430-P2 Ocu-Mir-430-P2 Pab-Mir-430-P2 Sha-Mir-430-P2 Spt-Mir-430-P2 Sto-Mir-430-P2 Tgu-Mir-430-P2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr4: 112648366-112648425 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-430-P2)

Mir-92-P2a chr4: 112647877-112647936 [-] UCSC Ensembl
Mir-430-P4 chr4: 112648006-112648066 [-] UCSC Ensembl
Mir-430-P3 chr4: 112648186-112648246 [-] UCSC Ensembl
Mir-430-P2 chr4: 112648366-112648425 [-] UCSC Ensembl
Mir-430-P1 chr4: 112648489-112648547 [-] UCSC Ensembl

Seed

AAGUGCU

Precursor
(pre-Mir +30nt flank)

ACGCUAACCUCAUUUGAAGGGAUCCCCUUUGCUUUAACAUGGGGGUACCUGCUGUGUGAAACAAAAGUAAGUGCUUCCAUGUUUCAGUGGAGGUGUCUCCAAGCCAGCACACCUUUUGUU

Get precursor sequence

Structure

        10          20         30        40        50         
ACGCUAACCUCAUUUGAA--  -|  CC    UG  UU             C    GUGUG 
                    GG GAU  CCUU  CU  AACAUGGGGGUAC UGCU     A
                    CC CUG  GGAG  GA  UUGUACCUUCGUG AUGA     A
UUGUUUUCCACACGACCGAA  U^  U-    GU  CU             A    AAACA 
.       110       100         90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut +2 on the 5p arm.

3' NTU

Motifs

UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-430-P2_5p* (predicted)

mirBase accession

MIMAT0000716

Sequence

0- GCUUUAACAUGGGGGUACCUGCU -23

Get sequence

Proposed targets

microrna.org: MIMAT0000716
TargetScanVert: hsa-miR-302c-5p
TargetMiner: hsa-miR-302c-5p
miRDB: MIMAT0000716

Mature sequence

Hsa-Mir-430-P2_3p

mirBase accession

MIMAT0000717

Sequence

37- UAAGUGCUUCCAUGUUUCAGUGG -60

Get sequence

Proposed targets

microrna.org: MIMAT0000717
TargetScanVert: hsa-miR-302c-3p.1
TargetMiner: hsa-miR-302c-3p
miRDB: MIMAT0000717