Mir-181-P2c

MirGeneDB ID

Hsa-Mir-181-P2c

Family name

MIR-181 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-181d

Paralogues

Hsa-Mir-181-P1a Hsa-Mir-181-P1b Hsa-Mir-181-P1c Hsa-Mir-181-P2a Hsa-Mir-181-P2b

Orthologues

Aca-Mir-181-P2c Ami-Mir-181-P2c Bta-Mir-181-P2c Cfa-Mir-181-P2c Cja-Mir-181-P2c Cmi-Mir-181-P2c Cpi-Mir-181-P2c Dno-Mir-181-P2c Dre-Mir-181-P2c1 Dre-Mir-181-P2c2 Eca-Mir-181-P2c Ete-Mir-181-P2c Gmo-Mir-181-P2c1 Gmo-Mir-181-P2c2 Laf-Mir-181-P2c Lch-Mir-181-P2c Loc-Mir-181-P2c Mal-Mir-181-P2c1 Mal-Mir-181-P2c2 Mdo-Mir-181-P2c Mml-Mir-181-P2c Mmr-Mir-181-P2c Mmu-Mir-181-P2c Mun-Mir-181-P2c Neu-Mir-181-P2c Oan-Mir-181-P2c Ocu-Mir-181-P2c Pab-Mir-181-P2c Pbv-Mir-181-P2c Rno-Mir-181-P2c Sha-Mir-181-P2c Spt-Mir-181-P2c3 Spt-Mir-181-P2c4 Sto-Mir-181-P2c Tni-Mir-181-P2c1-v1 Tni-Mir-181-P2c2

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chr19: 13874910-13874972 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-181-P2c)

Mir-24-P3 chr19: 13836289-13836348 [-] UCSC Ensembl
Mir-27-P3 chr19: 13836447-13836508 [-] UCSC Ensembl
Mir-23-P3 chr19: 13836593-13836651 [-] UCSC Ensembl
Mir-181-P1c chr19: 13874725-13874785 [+] UCSC Ensembl
Mir-181-P2c chr19: 13874910-13874972 [+] UCSC Ensembl

Seed

ACAUUCA

Precursor
(pre-Mir +30nt flank)

CUCCCCUAGGCCACAGCCGAGGUCACAAUCAACAUUCAUUGUUGUCGGUGGGUUGUGAGGACUGAGGCCAGACCCACCGGGGGAUGAAUGUCACUGUGGCUGGGCCAGACACGGCUUAAGGGG

Get precursor sequence

Structure

        10        20          30        40        50        60  
CUCCCCUAGGCCACAGCCGA--|      AUCA         G UG          GUGAGGA 
                      GGUCACA    ACAUUCAUU U  UCGGUGGGUU       C
                      UCGGUGU    UGUAAGUAG G  GGCCACCCAG       U
GGGGAAUUCGGCACAGACCGGG^      CAC-         G --          ACCGGAG 
 120       110       100         90          80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Mature sequence

Hsa-Mir-181-P2c_5p

mirBase accession

MIMAT0002821

Sequence

0- AACAUUCAUUGUUGUCGGUGGGUU -24

Get sequence

Proposed targets

microrna.org: MIMAT0002821
TargetScanVert: hsa-miR-181d-5p
miRDB: MIMAT0002821

Star sequence

Hsa-Mir-181-P2c_3p*

mirBase accession

MIMAT0026608

Sequence

43- CCACCGGGGGAUGAAUGUCA -63

Get sequence

Proposed targets

TargetScanVert: hsa-miR-181d-3p
miRDB: MIMAT0026608