Mir-10-P2b

MirGeneDB ID

Rno-Mir-10-P2b

Family name

MIR-10 (all species)

Species

Norway rat (Rattus norvegicus)

MiRBase ID

rno-mir-99b

Paralogues

Rno-Mir-10-P1b-v1 Rno-Mir-10-P1c-v1 Rno-Mir-10-P2c Rno-Mir-10-P2d Rno-Mir-10-P3b Rno-Mir-10-P3c Rno-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2b Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2b Asp-Mir-10 Bfl-Mir-10-P2-v1 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bpl-Mir-10-P2 Bta-Mir-10-P2b Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2b Cin-Mir-10-P2 Cja-Mir-10-P2b Cpi-Mir-10-P2b Cpo-Mir-10-P2b Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dpu-Mir-10-P2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2b Ete-Mir-10-P2b Gja-Mir-10-P2b Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2b Isc-Mir-10-P2 Laf-Mir-10-P2b Lan-Mir-10-P2 Lch-Mir-10-P2b Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Mgi-Mir-10-P2 Mml-Mir-10-P2b Mmr-Mir-10-P2b Mmu-Mir-10-P2b Mom-Mir-10-P2 Mun-Mir-10-P2b Neu-Mir-10-P2b Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2b Obi-Mir-10-P2 Ocu-Mir-10-P2b Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2b Pau-Mir-10-P2 Pbv-Mir-10-P2b Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rph-Mir-10-P2 Sha-Mir-10-P2b Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2b Sto-Mir-10-P2b Tca-Mir-10-P2 Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2b1 Xla-Mir-10-P2b2 Xtr-Mir-10-P2b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(rn6)

chr1: 59704222-59704281 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2b)

Mir-10-P2b chr1: 59704222-59704281 [+] UCSC Ensembl
Let-7-P1b chr1: 59704395-59704461 [+] UCSC Ensembl
Mir-10-P3b chr1: 59704841-59704900 [+] UCSC Ensembl

Seed

ACCCGUA

Precursor
(pre-Mir +30nt flank)

CGGGGGCCCGGACUCCUGGGUCCUGGCACCCACCCGUAGAACCGACCUUGCGGGGCCUUCGCCGCACACAAGCUCGUGUCUGUGGGUCCGUGUCGGGGGCUCACCAUCGCGGCUGGGACC

Get precursor sequence

Structure

        10         20         30        40        50         
CGGGGGCCCGGACUCCU-   -|        CC         AC   C    CGGGGCCU 
                  GGG UCCUGGCAC  ACCCGUAGA  CGA CUUG        U
                  CUC GGGGCUGUG  UGGGUGUCU  GCU GAAC        C
CCAGGGUCGGCGCUACCA   G^        CC         GU   C    ACACGCCG 
.       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14)

Tissue expression

Dr	Dr	Ad	Bi	Bi	Bi	Bi	Br	Br	Br	Br	Ce	Ce	Ce	Ce	Co	Co	Co	Co	Du	Du	Du	Du	Fa	He	He	He	Hi	Hi	Il	Il	Je	Je	Ki	Ki	Ki	Ki	Ki	La	Li	Li	Li	Li	Li	Li	Lu	Me	Me	Mu	Ov	Pa	Pa	Pa	Sk	Sm	So	So	So	So	Sp	St	St	St	St	Te	Te	Th	Ut	Wh

Mature sequence

Rno-Mir-10-P2b_5p

mirBase accession

MIMAT0000821

Sequence

0- CACCCGUAGAACCGACCUUGCG -22

Get sequence

Proposed targets

microrna.org: MIMAT0000821
TargetScanVert: rno-miR-99b-5p
miRDB: MIMAT0000821

Star sequence

Rno-Mir-10-P2b_3p*

mirBase accession

MIMAT0004725

Sequence

38- CAAGCUCGUGUCUGUGGGUCCG -60

Get sequence

Proposed targets

microrna.org: MIMAT0004725
TargetScanVert: rno-miR-99b-3p
miRDB: MIMAT0004725