Mir-10-P2b

MirGeneDB ID

Mml-Mir-10-P2b

Family name

MIR-10 (all species)

Species

Rhesus monkey (Macaca mulatta)

MiRBase ID

mml-mir-99b

Paralogues

Mml-Mir-10-P1b-v1 Mml-Mir-10-P1c-v1 Mml-Mir-10-P2c Mml-Mir-10-P2d Mml-Mir-10-P3b Mml-Mir-10-P3c Mml-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2b Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2b Asp-Mir-10 Bfl-Mir-10-P2-v1 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bpl-Mir-10-P2 Bta-Mir-10-P2b Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2b Cin-Mir-10-P2 Cja-Mir-10-P2b Cpi-Mir-10-P2b Cpo-Mir-10-P2b Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dpu-Mir-10-P2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2b Ete-Mir-10-P2b Gja-Mir-10-P2b Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2b Isc-Mir-10-P2 Laf-Mir-10-P2b Lan-Mir-10-P2 Lch-Mir-10-P2b Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Mgi-Mir-10-P2 Mmr-Mir-10-P2b Mmu-Mir-10-P2b Mom-Mir-10-P2 Mun-Mir-10-P2b Neu-Mir-10-P2b Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2b Obi-Mir-10-P2 Ocu-Mir-10-P2b Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2b Pau-Mir-10-P2 Pbv-Mir-10-P2b Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2b Rph-Mir-10-P2 Sha-Mir-10-P2b Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2b Sto-Mir-10-P2b Tca-Mir-10-P2 Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2b1 Xla-Mir-10-P2b2 Xtr-Mir-10-P2b

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCA_003339765.3_Mmul_10_traces)

CM014354.1: 51446707-51446766 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2b)

Mir-10-P2b CM014354.1: 51446707-51446766 [+] UCSC Ensembl
Let-7-P1b CM014354.1: 51446883-51446949 [+] UCSC Ensembl
Mir-10-P3b CM014354.1: 51447359-51447418 [+] UCSC Ensembl

Seed

ACCCGUA

Precursor
(pre-Mir +30nt flank)

CGGGGGCCCGGACUCCUGGGUCCUGGCACCCACCCGUAGAACCGACCUUGCGGGGCCUUCGCCGCACACAAGCUCGUGUCUGUGGGUCCGUGUCGGGGGCUCACCAUCGCGGCUGGGGCC

Get precursor sequence

Structure

        10         20         30        40        50         
CGGGGGCCCGGACUCCU-   -|        CC         AC   C    CGGGGCCU 
                  GGG UCCUGGCAC  ACCCGUAGA  CGA CUUG        U
                  CUC GGGGCUGUG  UGGGUGUCU  GCU GAAC        C
CCGGGGUCGGCGCUACCA   G^        CC         GU   C    ACACGCCG 
.       110       100        90        80        70        60

Deep sequencing

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Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14)

Tissue expression

Bo	Br	Br	Br	He	Ki	Li	Lu	Ly	Sk	Sp	Te	Th

Mature sequence

Mml-Mir-10-P2b_5p

mirBase accession

MIMAT0006179

Sequence

0- CACCCGUAGAACCGACCUUGCG -22

Get sequence

Proposed targets

TargetScanVert: mml-miR-99b-5p

Star sequence

Mml-Mir-10-P2b_3p*

mirBase accession

MIMAT0026812

Sequence

38- CAAGCUCGUGUCUGUGGGUCCG -60

Get sequence

Proposed targets

TargetScanVert: mml-miR-99b-3p