Mir-19-P1a

MirGeneDB ID

Gga-Mir-19-P1a

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Chicken (Gallus gallus)

MiRBase ID

gga-mir-19a

Paralogues

Gga-Mir-19-P2a Gga-Mir-19-P2c

Orthologues

Aca-Mir-19-P1a Ami-Mir-19-P1a Bta-Mir-19-P1a Cfa-Mir-19-P1a Cli-Mir-19-P1a Cmi-Mir-19-P1a-v1 Cmi-Mir-19-P1a-v2 Cpi-Mir-19-P1a Cpo-Mir-19-P1a Dno-Mir-19-P1a Dre-Mir-19-P1a1 Dre-Mir-19-P1a2 Ete-Mir-19-P1a Gja-Mir-19-P1a Gmo-Mir-19-P1a1 Gmo-Mir-19-P1a2 Hsa-Mir-19-P1a Lch-Mir-19-P1a Loc-Mir-19-P1a Mal-Mir-19-P1a2 Mdo-Mir-19-P1a Mml-Mir-19-P1a Mmu-Mir-19-P1a Mun-Mir-19-P1a Oan-Mir-19-P1a Ocu-Mir-19-P1a Pbv-Mir-19-P1a Rno-Mir-19-P1a Sha-Mir-19-P1a Spt-Mir-19-P1a Sto-Mir-19-P1a-v1 Sto-Mir-19-P1a-v2 Tgu-Mir-19-P1a Tni-Mir-19-P1a1 Tni-Mir-19-P1a2 Xla-Mir-19-P1a3 Xla-Mir-19-P1a4 Xtr-Mir-19-P1a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(Gallus_gallus.GRCg6a)

1: 149440280-149440337 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P1a)

Mir-92-P1a 1: 149439857-149439915 [-] UCSC Ensembl
Mir-19-P2a 1: 149439972-149440032 [-] UCSC Ensembl
Mir-17-P4a 1: 149440105-149440163 [-] UCSC Ensembl
Mir-19-P1a 1: 149440280-149440337 [-] UCSC Ensembl
Mir-17-P2a 1: 149440419-149440483 [-] UCSC Ensembl
Mir-17-P1a 1: 149440570-149440630 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CAGUAGCUUUCUGCUUUGCAGUCUUCUGUUAGUUUUGCAUAGUUGCACUACAGGAAGAAUGUAGUUGUGCAAAUCUAUGCAAAACUGAUGGUGGCCUGUUAUAAUCUACAUCAAGGAG

Get precursor sequence

Structure

        10          20        30        40          50       
CAGUAGCUUUCUGCUUU--    U  U                 --|     U  AGGAA 
                   GCAG CU CUGUUAGUUUUGCAUAG  UUGCAC AC     G
                   UGUC GG GGUAGUCAAAACGUAUC  AACGUG UG     A
GAGGAACUACAUCUAAUAU    C  U                 UA^     U  AUGUA 
      110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut -3 on the 5p arm.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Ad	Ad	Ad	Br	Br	Ce	Ce	Ce	Ce	Ch	He	He	Hy	Hy	Ki	Ki	Li	Li	Lu	Lu	Ov	Pr	Pr	Sc	Sc	Sp	Sp	Te

Star sequence

Gga-Mir-19-P1a_5p*

mirBase accession

MIMAT0026498

Sequence

0- AGUUUUGCAUAGUUGCACUAC -21

Get sequence

Proposed targets

TargetScanVert: gga-miR-19a-5p
miRDB: MIMAT0026498

Mature sequence

Gga-Mir-19-P1a_3p

mirBase accession

MIMAT0001112

Sequence

35- UGUGCAAAUCUAUGCAAAACUGA -58

Get sequence

Proposed targets

TargetScanVert: gga-miR-19a-3p
miRDB: MIMAT0001112