Mir-19-P1a1

MirGeneDB ID

Tni-Mir-19-P1a1

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Pufferfish (Tetraodon nigroviridis)

MiRBase ID

tni-mir-19a

Paralogues

Tni-Mir-19-P1a2 Tni-Mir-19-P2a1 Tni-Mir-19-P2a2 Tni-Mir-19-P2d

Orthologues

Aca-Mir-19-P1a Ami-Mir-19-P1a Bta-Mir-19-P1a Cfa-Mir-19-P1a Cli-Mir-19-P1a Cmi-Mir-19-P1a-v1 Cmi-Mir-19-P1a-v2 Cpi-Mir-19-P1a Cpo-Mir-19-P1a Dno-Mir-19-P1a Dre-Mir-19-P1a1 Ete-Mir-19-P1a Gga-Mir-19-P1a Gja-Mir-19-P1a Gmo-Mir-19-P1a1 Hsa-Mir-19-P1a Lch-Mir-19-P1a Loc-Mir-19-P1a Mdo-Mir-19-P1a Mml-Mir-19-P1a Mmu-Mir-19-P1a Mun-Mir-19-P1a Oan-Mir-19-P1a Ocu-Mir-19-P1a Pbv-Mir-19-P1a Rno-Mir-19-P1a Sha-Mir-19-P1a Spt-Mir-19-P1a Sto-Mir-19-P1a-v1 Sto-Mir-19-P1a-v2 Tgu-Mir-19-P1a Xtr-Mir-19-P1a

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Vertebrata

Genome context
(Tetraodon_nigroviridis.TETRAODON8.dna.toplevel)

5: 8188599-8188656 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P1a1)

Mir-92-P1a1 5: 8188110-8188167 [-] UCSC Ensembl
Mir-19-P2a1 5: 8188261-8188319 [-] UCSC Ensembl
Mir-19-P1a1 5: 8188599-8188656 [-] UCSC Ensembl
Mir-17-P2a1 5: 8188734-8188798 [-] UCSC Ensembl
Mir-17-P1a1 5: 8188866-8188926 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UUGGGCCCAAAUAUCUUGCAGUUCUCUGCUAGUUUUGCAUAGUUGCACUACAAGAAUAGAGGAGUUGUGCAAAUCUAUGCAAAACUGAUGGUGGCCUGCUUGCUCUCCACCUGGUACG

Get precursor sequence

Structure

        10          20        30        40          50       
UUGGGCCCAAAUAUCUU--    UU U  GC             --|     U  AAGAA 
                   GCAG  C CU  UAGUUUUGCAUAG  UUGCAC AC     U
                   CGUC  G GG  GUCAAAACGUAUC  AACGUG UG     A
GCAUGGUCCACCUCUCGUU    CG U  UA             UA^     U  AGGAG 
      110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There are Drosha cuts -1 and -3 on the 5p arm.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Sp	Sp	Sp	To

Star sequence

Tni-Mir-19-P1a1_5p*

mirBase accession

None

Sequence

0- AGUUUUGCAUAGUUGCACUAC -21

Get sequence

Mature sequence

Tni-Mir-19-P1a1_3p

mirBase accession

MIMAT0002921

Sequence

35- UGUGCAAAUCUAUGCAAAACUGA -58

Get sequence