Mir-19-P1a1

MirGeneDB ID

Dre-Mir-19-P1a1

Family name

MIR-19 (all species)

Seed

GUGCAAA

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-mir-19a

Paralogues

Dre-Mir-19-P1a2 Dre-Mir-19-P2a1 Dre-Mir-19-P2a2 Dre-Mir-19-P2c Dre-Mir-19-P2d

Orthologues

Aca-Mir-19-P1a Ami-Mir-19-P1a Bta-Mir-19-P1a Cfa-Mir-19-P1a Cli-Mir-19-P1a Cmi-Mir-19-P1a-v1 Cmi-Mir-19-P1a-v2 Cpi-Mir-19-P1a Cpo-Mir-19-P1a Dno-Mir-19-P1a Ete-Mir-19-P1a Gga-Mir-19-P1a Gja-Mir-19-P1a Gmo-Mir-19-P1a1 Hsa-Mir-19-P1a Lch-Mir-19-P1a Loc-Mir-19-P1a Mdo-Mir-19-P1a Mml-Mir-19-P1a Mmu-Mir-19-P1a Mun-Mir-19-P1a Oan-Mir-19-P1a Ocu-Mir-19-P1a Pbv-Mir-19-P1a Rno-Mir-19-P1a Sha-Mir-19-P1a Spt-Mir-19-P1a Sto-Mir-19-P1a-v1 Sto-Mir-19-P1a-v2 Tgu-Mir-19-P1a Tni-Mir-19-P1a1 Xtr-Mir-19-P1a

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Vertebrata

Genome context
(danRer11)

chr1: 3297862-3297919 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-19-P1a1)

Mir-92-P1a1 chr1: 3297377-3297435 [-] UCSC Ensembl
Mir-19-P2a1 chr1: 3297494-3297555 [-] UCSC Ensembl
Mir-17-P4a1 chr1: 3297646-3297705 [-] UCSC Ensembl
Mir-19-P1a1 chr1: 3297862-3297919 [-] UCSC Ensembl
Mir-17-P2a1 chr1: 3298014-3298078 [-] UCSC Ensembl
Mir-17-P1a1 chr1: 3298149-3298209 [-] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

UCAUUUUUUCUUUUGGUGCAGUUCUCUGCUAGUUUUGCAUAGUUGCACUACAAGAAAACGGGAGUUGUGCAAAUCUAUGCAAAACUGAUGGUGGCCUGCUGCUUCUCCACGAUUCCCA

Get precursor sequence

Structure

        10          20        30        40          50       
UCAUUUUUUCUUUUGGU--    UU U  GC             --|     U  AAGAA 
                   GCAG  C CU  UAGUUUUGCAUAG  UUGCAC AC     A
                   CGUC  G GG  GUCAAAACGUAUC  AACGUG UG     A
ACCCUUAGCACCUCUUCGU    CG U  UA             UA^     U  AGGGC 
      110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut -3 on the 5p arm.

3' NTU

Motifs

UG at 5p(-14), CNNC at 3p(+17)

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Star sequence

Dre-Mir-19-P1a1_5p*

mirBase accession

MIMAT0003398

Sequence

0- AGUUUUGCAUAGUUGCACUAC -21

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Mature sequence

Dre-Mir-19-P1a1_3p

mirBase accession

MIMAT0001782

Sequence

35- UGUGCAAAUCUAUGCAAAACUGA -58

Get sequence

Proposed targets

TargetScanFish: dre-miR-19a