Mir-22-o1b

MirGeneDB ID

Bla-Mir-22-o1b

Family name

MIR-22 (all species)

Seed

CAGCUCC

Species

European lancelet (Branchiostoma lanceolatum)

MiRBase ID

Paralogues

Bla-Mir-22-o1a Bla-Mir-22-o1c Bla-Mir-22-o3a1a Bla-Mir-22-o3a1b Bla-Mir-22-o3a1c Bla-Mir-22-o3a1d Bla-Mir-22-o3a2a Bla-Mir-22-o3a2b Bla-Mir-22-o3a3 Bla-Mir-22-o3b1 Bla-Mir-22-o3b2 Bla-Mir-22-o3b3 Bla-Mir-22-o3c1 Bla-Mir-22-o3c2 Bla-Mir-22-P1

Orthologues

Aca-Mir-22-P1b Ami-Mir-22-P1b Bfl-Mir-22-o1b Bfl-Mir-22-P1 Bpl-Mir-22-P1 Bta-Mir-22-P1b Cfa-Mir-22-P1b Cgi-Mir-22-P1 Cli-Mir-22-P1b Cmi-Mir-22-P1b Cpi-Mir-22-P1b Cpo-Mir-22-P1b Cte-Mir-22-P1 Dno-Mir-22-P1b Dre-Mir-22-P1b1 Dre-Mir-22-P1b2 Esc-Mir-22-P1 Ete-Mir-22-P1b Gga-Mir-22-P1b Gja-Mir-22-P1b Gmo-Mir-22-P1b1 Gmo-Mir-22-P1b2 Hsa-Mir-22-P1b Lan-Mir-22-P1 Lch-Mir-22-P1b Lgi-Mir-22-P1 Loc-Mir-22-P1b Mal-Mir-22-P1b1 Mal-Mir-22-P1b2 Mdo-Mir-22-P1b Mml-Mir-22-P1b Mmu-Mir-22-P1b Mun-Mir-22-P1b Npo-Mir-22-P1 Oan-Mir-22-P1b Obi-Mir-22-P1 Ocu-Mir-22-P1b Ovu-Mir-22-P1 Pbv-Mir-22-P1b Pfl-Mir-22-P1 Rno-Mir-22-P1b Sha-Mir-22-P1b Sme-Mir-22-P1 Spt-Mir-22-P1b Sto-Mir-22-P1b Tgu-Mir-22-P1b Tni-Mir-22-P1b1 Tni-Mir-22-P1b2 Xla-Mir-22-P1b3 Xla-Mir-22-P1b4 Xtr-Mir-22-P1b

Node of Origin (locus)

Branchiostoma

Node of Origin (family)

Bilateria

Genome context
(BraLan2)

Sc0000017: 1346304-1346363 [-] Ensembl

Precursor
(pre-Mir +30nt flank)

CUUUUCUGUAUCGUAAGCGUGUCAGCUUCCCUCAUCACACCGGAAGCUGUUACGUCACUUCCGUUGUAUCAGCUCCAGCUGUGAUGAGUGAAGAGGCAUGCGCAGAACAACAAACCAACG

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Structure

        10           20        30        40         50         
CUUUUCUGUAUCGUAAG---|     AG    C         CC-   A    U  CGUCAC 
                    CGUGUC  CUUC CUCAUCACA   GGA GCUG UA      U
                    GUACGG  GAAG GAGUAGUGU   CCU CGAC AU      U
GCAACCAAACAACAAGACGC^     A-    U         CGA   -    U  GUUGCC 
.       110       100         90        80         70        60

Deep sequencing

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Comment

It is unclear if this paralogue group represents the ancestral Mir-22-P2 gene that is seed shifted or a new paralogue derived from the ancestral P1 gene. It is also unclear if this gene is orthologous to the Mir-22-o2 gene in ambulacrarians.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Ad	Ad	Em	Em	Em	Em

Star sequence

Bla-Mir-22-o1b_5p*

mirBase accession

None

Sequence

0- CUCAUCACACCGGAAGCUGUUA -22

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Mature sequence

Bla-Mir-22-o1b_3p

mirBase accession

None

Sequence

38- UCAGCUCCAGCUGUGAUGAGUG -60

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