MirGeneDB 3.0

MirGeneDB ID

Rno-Mir-221-P1a

Family name MIR-221 (all species)
Species Norway rat (Rattus norvegicus)
MiRBase ID rno-mir-222
Paralogues Rno-Mir-221-P2a 
Orthologues Aca-Mir-221-P1a  Ami-Mir-221-P1a  Bta-Mir-221-P1a  Cfa-Mir-221-P1a  Cja-Mir-221-P1a1  Cja-Mir-221-P1a2  Cli-Mir-221-P1a  Cmi-Mir-221-P1a  Cpi-Mir-221-P1a  Cpo-Mir-221-P1a  Dno-Mir-221-P1a  Dre-Mir-221-P1a1  Eca-Mir-221-P1a  Ete-Mir-221-P1a  Gga-Mir-221-P1a  Gja-Mir-221-P1a  Gmo-Mir-221-P1a1  Gmo-Mir-221-P1a2  Hsa-Mir-221-P1a  Laf-Mir-221-P1a  Lch-Mir-221-P1a  Loc-Mir-221-P1a  Mal-Mir-221-P1a1  Mal-Mir-221-P1a2  Mdo-Mir-221-P1a  Mml-Mir-221-P1a  Mmr-Mir-221-P1a  Mmu-Mir-221-P1a  Mun-Mir-221-P1a  Neu-Mir-221-P1a  Oan-Mir-221-P1a  Ocu-Mir-221-P1a  Pab-Mir-221-P1a  Pbv-Mir-221-P1a  Sha-Mir-221-P1a  Spt-Mir-221-P1a  Sto-Mir-221-P1a  Tgu-Mir-221-P1a  Tni-Mir-221-P1a1  Xla-Mir-221-P1a3  Xla-Mir-221-P1a4  Xtr-Mir-221-P1a 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(rn6)
chrX: 3683940-3684003 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-221-P1a)
Mir-221-P1a chrX: 3683940-3684003 [+] UCSC Ensembl
Mir-221-P2a chrX: 3684504-3684566 [+] UCSC Ensembl
Seed GCUACAU
Precursor
(pre-Mir +30nt flank)
AGCUCUCAAAAGGAUUAGGGUGCCCUCAGUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUGGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCAUCUAGCUUCAGCUGUGGUA
Get precursor sequence
Structure
        10          20        30        40         50        60 
AGCUCUCAAAAGGAUUAG--      C    U              -|    AUCCUGUCUUU 
                    GGUGCC UCAG GGCUCAGUAGCCAG UGUAG           \
                    CUACGG AGUC CUGGGUCAUCGGUC ACAUC           G
AUGGUGUCGACUUCGAUCUA      U    U              U^    GACGACUAAUG 
  120       110       100        90        80        70
Deep sequencing
Go to detailed chart
3' NTU No
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
- +
Dr Dr Ad Bi Bi Bi Bi Br Br Br Br Ce Ce Ce Ce Co Co Co Co Du Du Du Du Fa He He He Hi Hi Il Il Je Je Ki Ki Ki Ki Ki La Li Li Li Li Li Li Lu Me Me Mu Ov Pa Pa Pa Sk Sm So So So So Sp St St St St Te Te Th Ut Wh
Star sequence

Rno-Mir-221-P1a_5p*

mirBase accessionMIMAT0017164
Sequence
0- GGCUCAGUAGCCAGUGUAGAUCC -23
Get sequence
Proposed targets TargetScanVert: rno-miR-222-5p
miRDB: MIMAT0017164
Mature sequence

Rno-Mir-221-P1a_3p

mirBase accessionMIMAT0000891
Sequence
40- AGCUACAUCUGGCUACUGGGUCUC -64
Get sequence
Proposed targets microrna.org: MIMAT0000891
TargetScanVert: rno-miR-222-3p
miRDB: MIMAT0000891