MirGeneDB 3.0
MirGeneDB ID

Xla-Mir-221-P1a4

Family name MIR-221 (all species)
Species African clawed frog (Xenopus laevis)
MiRBase ID xla-mir-222
Paralogues Xla-Mir-221-P1a3  Xla-Mir-221-P2a3  Xla-Mir-221-P2a4 
Orthologues Aca-Mir-221-P1a  Ami-Mir-221-P1a  Bta-Mir-221-P1a  Cfa-Mir-221-P1a  Cli-Mir-221-P1a  Cmi-Mir-221-P1a  Cpi-Mir-221-P1a  Cpo-Mir-221-P1a  Dno-Mir-221-P1a  Eca-Mir-221-P1a  Ete-Mir-221-P1a  Gga-Mir-221-P1a  Gja-Mir-221-P1a  Hsa-Mir-221-P1a  Laf-Mir-221-P1a  Lch-Mir-221-P1a  Loc-Mir-221-P1a  Mdo-Mir-221-P1a  Mml-Mir-221-P1a  Mmr-Mir-221-P1a  Mmu-Mir-221-P1a  Mun-Mir-221-P1a  Neu-Mir-221-P1a  Oan-Mir-221-P1a  Ocu-Mir-221-P1a  Pab-Mir-221-P1a  Pbv-Mir-221-P1a  Rno-Mir-221-P1a  Sha-Mir-221-P1a  Spt-Mir-221-P1a  Sto-Mir-221-P1a  Tgu-Mir-221-P1a  Xtr-Mir-221-P1a 
Node of Origin (locus) X. laevis
Node of Origin (family) Vertebrata
Genome context
(GCF_001663975.1_XLA_v2)		 NC_030727.1: 44885774-44885835 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-221-P1a4)		 Mir-221-P1a4 NC_030727.1: 44885774-44885835 [+] UCSC Ensembl
Mir-221-P2a4 NC_030727.1: 44886234-44886296 [+] UCSC Ensembl
Seed GCUACAU
Precursor
(pre-Mir +30nt flank)		 
UAUUUCCAAAAUGUUAACACUGGGGUUAUUCGCUCAGUAAUCAGUGUAGAUCCUGUAUUUCUGUCAGCAGCUACAUCUGGCUACUGGGUCUCUAACUCCAUUGCCUCUGCUCAGGAUGAUUG
Get precursor sequence
Structure
        10          20        30        40         50          
UAUUUCCAAAAUGUUAA--  C        UUC        AU   -|    AUCCUGUAUU 
                   CA UGGGGUUA   GCUCAGUA  CAG UGUAG          \
                   GU ACCUCAAU   UGGGUCAU  GUC ACAUC          U
GUUAGUAGGACUCGUCUCC  U        CUC        CG   U^    GACGACUGUC 
120       110       100        90        80        70
Deep sequencing
3' NTU No
MotifsUGUG in loop
Tissue expression
- +
Em
Star sequence

Xla-Mir-221-P1a4_5p*
mirBase accessionMIMAT0046544
Sequence 
0- CGCUCAGUAAUCAGUGUAGAUCC -23
Get sequence
Mature sequence

Xla-Mir-221-P1a4_3p
mirBase accessionMIMAT0046545
Sequence 
38- AGCUACAUCUGGCUACUGGGUCUC -62
Get sequence