Mir-221-P1a

MirGeneDB ID

Mdo-Mir-221-P1a

Family name

MIR-221 (all species)

Seed

GCUACAU

Species

Gray short-tailed opossum (Monodelphis domestica)

MiRBase ID

mdo-mir-222a

Paralogues

Mdo-Mir-221-P2a

Orthologues

Aca-Mir-221-P1a Ami-Mir-221-P1a Bta-Mir-221-P1a Cfa-Mir-221-P1a Cli-Mir-221-P1a Cmi-Mir-221-P1a Cpi-Mir-221-P1a Cpo-Mir-221-P1a Dno-Mir-221-P1a Dre-Mir-221-P1a1 Ete-Mir-221-P1a Gga-Mir-221-P1a Gja-Mir-221-P1a Gmo-Mir-221-P1a1 Gmo-Mir-221-P1a2 Hsa-Mir-221-P1a Lch-Mir-221-P1a Loc-Mir-221-P1a Mal-Mir-221-P1a1 Mal-Mir-221-P1a2 Mml-Mir-221-P1a Mmu-Mir-221-P1a Mun-Mir-221-P1a Oan-Mir-221-P1a Ocu-Mir-221-P1a Pbv-Mir-221-P1a Rno-Mir-221-P1a Sha-Mir-221-P1a Spt-Mir-221-P1a Sto-Mir-221-P1a Tgu-Mir-221-P1a Tni-Mir-221-P1a1 Xla-Mir-221-P1a3 Xla-Mir-221-P1a4 Xtr-Mir-221-P1a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(monDom5_add)

4: 17426702-17426765 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-221-P1a)

Mir-221-P1a 4: 17426702-17426765 [+] UCSC Ensembl
Mir-221-P2a 4: 17427286-17427348 [+] UCSC Ensembl

Precursor
(pre-Mir +30nt flank)

CGGUUCCCUCUGCCUAUUUUGUCCCUCAUUCGCUCAGUAGUCAGUGUAGAUACUGUCUCUUUCCAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUAGAGCUUCUGUCCCAACU

Get precursor sequence

Structure

        10           20        30        40         50        60 
CGGUUCCCUCUGCCUAUUU---| U  C   UUC             -     AUACUGUCUCU 
                      UG CC UCA   GCUCAGUAGUCAG UGUAG           \
                      AC GG AGU   UGGGUCAUCGGUC ACAUC           U
UCAACCCUGUCUUCGAGAUUCU^ -  U   CUC             U     GACGACUACCU 
  120       110        100        90        80        70

Deep sequencing

Go to detailed chart

Comment

Mirbase gives an incorrect structure for this sequence.

3' NTU

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Br	Ce	He	Ki	Te

Star sequence

Mdo-Mir-221-P1a_5p*

mirBase accession

MIMAT0004159

Sequence

0- CGCUCAGUAGUCAGUGUAGAUAC -23

Get sequence

Proposed targets

TargetScanVert: mdo-miR-222a

Mature sequence