Mir-221-P1a

MirGeneDB ID

Hsa-Mir-221-P1a

Family name

MIR-221 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-222

Paralogues

Hsa-Mir-221-P2a

Orthologues

Aca-Mir-221-P1a Ami-Mir-221-P1a Bta-Mir-221-P1a Cfa-Mir-221-P1a Cja-Mir-221-P1a1 Cja-Mir-221-P1a2 Cli-Mir-221-P1a Cmi-Mir-221-P1a Cpi-Mir-221-P1a Cpo-Mir-221-P1a Dno-Mir-221-P1a Dre-Mir-221-P1a1 Eca-Mir-221-P1a Ete-Mir-221-P1a Gga-Mir-221-P1a Gja-Mir-221-P1a Gmo-Mir-221-P1a1 Gmo-Mir-221-P1a2 Laf-Mir-221-P1a Lch-Mir-221-P1a Loc-Mir-221-P1a Mal-Mir-221-P1a1 Mal-Mir-221-P1a2 Mdo-Mir-221-P1a Mml-Mir-221-P1a Mmr-Mir-221-P1a Mmu-Mir-221-P1a Mun-Mir-221-P1a Neu-Mir-221-P1a Oan-Mir-221-P1a Ocu-Mir-221-P1a Pab-Mir-221-P1a Pbv-Mir-221-P1a Rno-Mir-221-P1a Sha-Mir-221-P1a Spt-Mir-221-P1a Sto-Mir-221-P1a Tgu-Mir-221-P1a Tni-Mir-221-P1a1 Xla-Mir-221-P1a3 Xla-Mir-221-P1a4 Xtr-Mir-221-P1a

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Vertebrata

Genome context
(hg38)

chrX: 45747033-45747096 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-221-P1a)

Mir-221-P2a chrX: 45746180-45746242 [-] UCSC Ensembl
Mir-221-P1a chrX: 45747033-45747096 [-] UCSC Ensembl

Seed

GCUACAU

Precursor
(pre-Mir +30nt flank)

CAGCUGCUGGAAGGUGUAGGUACCCUCAAUGGCUCAGUAGCCAGUGUAGAUCCUGUCUUUCGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUUCUAGCUUCUGCUUCAGUG

Get precursor sequence

Structure

        10          20        30        40         50        60 
CAGCUGCUGGAAGGUGU--    A  C   AU              -|    AUCCUGUCUUU 
                   AGGU CC UCA  GGCUCAGUAGCCAG UGUAG           \
                   UCUA GG AGU  CUGGGUCAUCGGUC ACAUC           C
GUGACUUCGUCUUCGAUCU    C  U   CU              U^    GACGACUAAUG 
  120       110       100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-221-P1a_5p*

mirBase accession

MIMAT0004569

Sequence

0- GGCUCAGUAGCCAGUGUAGAUCC -23

Get sequence

Proposed targets

microrna.org: MIMAT0004569
TargetScanVert: hsa-miR-222-5p
TargetMiner: hsa-miR-222-5p
miRDB: MIMAT0004569

Mature sequence

Hsa-Mir-221-P1a_3p

mirBase accession

MIMAT0000279

Sequence

40- AGCUACAUCUGGCUACUGGGUCUC -64

Get sequence

Proposed targets

microrna.org: MIMAT0000279
TargetScanVert: hsa-miR-222-3p
TargetMiner: hsa-miR-222-3p
miRDB: MIMAT0000279