MirGeneDB 3.0

MirGeneDB ID

Laf-Mir-221-P1a

Family name MIR-221 (all species)
Species African bush elephant (Loxodonta africana)
MiRBase ID
Paralogues Laf-Mir-221-P2a 
Orthologues Aca-Mir-221-P1a  Ami-Mir-221-P1a  Bta-Mir-221-P1a  Cfa-Mir-221-P1a  Cja-Mir-221-P1a1  Cja-Mir-221-P1a2  Cli-Mir-221-P1a  Cmi-Mir-221-P1a  Cpi-Mir-221-P1a  Cpo-Mir-221-P1a  Dno-Mir-221-P1a  Dre-Mir-221-P1a1  Eca-Mir-221-P1a  Ete-Mir-221-P1a  Gga-Mir-221-P1a  Gja-Mir-221-P1a  Gmo-Mir-221-P1a1  Gmo-Mir-221-P1a2  Hsa-Mir-221-P1a  Lch-Mir-221-P1a  Loc-Mir-221-P1a  Mal-Mir-221-P1a1  Mal-Mir-221-P1a2  Mdo-Mir-221-P1a  Mml-Mir-221-P1a  Mmr-Mir-221-P1a  Mmu-Mir-221-P1a  Mun-Mir-221-P1a  Neu-Mir-221-P1a  Oan-Mir-221-P1a  Ocu-Mir-221-P1a  Pab-Mir-221-P1a  Pbv-Mir-221-P1a  Rno-Mir-221-P1a  Sha-Mir-221-P1a  Spt-Mir-221-P1a  Sto-Mir-221-P1a  Tgu-Mir-221-P1a  Tni-Mir-221-P1a1  Xla-Mir-221-P1a3  Xla-Mir-221-P1a4  Xtr-Mir-221-P1a 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Vertebrata
Genome context
(GCA_000001905.1_Loxafr3.0)
GL010083.1: 5382008-5382071 [+] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-221-P1a)
Mir-221-P1a GL010083.1: 5382008-5382071 [+] UCSC Ensembl
Mir-221-P2a GL010083.1: 5382694-5382756 [+] UCSC Ensembl
Seed GCUACAU
Precursor
(pre-Mir +30nt flank)
AUGUGCUGGAAUGUGUAGUUGCCCCUCAAUGGCUCAGUAGCUAGUGUAGAUCCUGUCUUUUGUAAUCAGCAGCUACAUCUGGCUACUGGGUCUCUGAUGGCAUCUCCUAGCUUCUGUCACAGUG
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Structure
        10           20        30        40         50        60 
AUGUGCUGGAAUGUGUA---|U    CC   AU              -     AUCCUGUCUUU 
                    G UGCC  UCA  GGCUCAGUAGCUAG UGUAG           \
                    C ACGG  AGU  CUGGGUCAUCGGUC ACAUC           U
GUGACACUGUCUUCGAUCCU^U    U-   CU              U     GACGACUAAUG 
  120       110       100         90        80        70
Deep sequencing
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CommentThere is a second Drosha cut +2 on the 5p arm.
3' NTU No
MotifsCNNC at 3p(+17), UGUG in loop
Tissue expression
- +
Wh
Star sequence

Laf-Mir-221-P1a_5p* (predicted)

mirBase accessionNone
Sequence
0- GGCUCAGUAGCUAGUGUAGAUCC -23
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Mature sequence

Laf-Mir-221-P1a_3p

mirBase accessionNone
Sequence
40- AGCUACAUCUGGCUACUGGGUCUC -64
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