MirGeneDB 2.1

MirGeneDB ID

Pbv-Mir-10-P2c

Family name MIR-10 (all species)
Seed ACCCGUA
Species Burmese python (Python bivittatus)
MiRBase ID pbv-mir-99a
Paralogues Pbv-Mir-10-P1b-v1  Pbv-Mir-10-P1b-v2  Pbv-Mir-10-P1c-v1  Pbv-Mir-10-P1c-v2  Pbv-Mir-10-P1d-v1  Pbv-Mir-10-P1d-v2  Pbv-Mir-10-P2b  Pbv-Mir-10-P2d  Pbv-Mir-10-P3b  Pbv-Mir-10-P3c  Pbv-Mir-10-P3d 
Orthologues Aae-Mir-10-P2  Aca-Mir-10-P2c  Ami-Mir-10-P2c  Bfl-Mir-10-P2-v1  Bfl-Mir-10-P2-v2  Bge-Mir-10-P2  Bla-Mir-10-P2-v1  Bla-Mir-10-P2-v2  Bpl-Mir-10-P2  Bta-Mir-10-P2c  Cbr-Mir-10-P2  Cel-Mir-10-P2  Cfa-Mir-10-P2c  Cgi-Mir-10-P2  Cin-Mir-10-P2  Cli-Mir-10-P2c  Cmi-Mir-10-P2c  Cpi-Mir-10-P2c  Cpo-Mir-10-P2c  Cte-Mir-10-P2  Dan-Mir-10-P2  Dma-Mir-10-P2  Dme-Mir-10-P2  Dmo-Mir-10-P2  Dno-Mir-10-P2c  Dpu-Mir-10-P2  Dre-Mir-10-P2c1  Dre-Mir-10-P2c2  Dsi-Mir-10-P2  Dya-Mir-10-P2  Ete-Mir-10-P2c  Gga-Mir-10-P2c  Gja-Mir-10-P2c  Gmo-Mir-10-P2c2  Hsa-Mir-10-P2c  Isc-Mir-10-P2  Lan-Mir-10-P2  Lch-Mir-10-P2c  Lgi-Mir-10-P2  Loc-Mir-10-P2c  Mal-Mir-10-P2c2  Mml-Mir-10-P2c  Mmu-Mir-10-P2c  Mun-Mir-10-P2c  Npo-Mir-10-P2  Nve-Mir-10  Oan-Mir-10-P2c  Obi-Mir-10-P2  Ocu-Mir-10-P2c  Ovu-Mir-10-P2  Pfl-Mir-10-P2  Pmi-Mir-10-P2  Rno-Mir-10-P2c  Sha-Mir-10-P2c  Sko-Mir-10-P2  Spt-Mir-10-P2c  Sto-Mir-10-P2c  Tca-Mir-10-P2  Tgu-Mir-10-P2c  Xbo-Mir-10-P2  Xbo-Mir-10-P2-as  Xla-Mir-10-P2c3  Xla-Mir-10-P2c4  Xtr-Mir-10-P2c 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Eumetazoa
Genome context
(GCA_000186305.2_Python_molurus_bivittatus)
KE953041.1: 91452-91510 [+]
Clustered miRNAs
(< 50kb from Mir-10-P2c)
Mir-10-P2c KE953041.1: 91452-91510 [+]
Let-7-P1c KE953041.1: 92848-92913 [+]
Mir-10-P3c KE953041.1: 123184-123245 [+]
Precursor
(pre-Mir +30nt flank)
AACUUGUUUCCAUUGGUGCCAAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAAUAUAGUGCACAAGCUCGUUUCUAUGGGUCAGUGUCAGUCUGGUGAUUUAACAAGAUUGUAU
Get precursor sequence
Structure
        10         20         30        40        50         
AACUUGUUUCCAUUGGU-    -|       AA         UC   U      GUGAAA 
                  GCCA AUUGGCAU  ACCCGUAGA  CGA CUUGUG      \
                  UGGU UGACUGUG  UGGGUAUCU  GCU GAACAC      U
UAUGUUAGAACAAUUUAG    C^       AC         UU   C      GUGAUA 
       110       100        90        80        70        60
Deep sequencing
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CommentBased on the 3' moR reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.
3' NTU Yes
MotifsUG at 5p(-14), UGUG in loop
Tissue expression
 +
To
Mature sequence

Pbv-Mir-10-P2c_5p

mirBase accessionMIMAT0038895
Sequence
0- AACCCGUAGAUCCGAUCUUGUG -22
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Star sequence

Pbv-Mir-10-P2c_3p*

mirBase accessionMIMAT0038896
Sequence
37- CAAGCUCGUUUCUAUGGGUCAG -59
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