MirGeneDB 3.0
MirGeneDB ID

Laf-Mir-10-P2c

Family name MIR-10 (all species)
Species African bush elephant (Loxodonta africana)
MiRBase ID
Paralogues Laf-Mir-10-P1b  Laf-Mir-10-P1c-v1  Laf-Mir-10-P2b  Laf-Mir-10-P2d  Laf-Mir-10-P3b  Laf-Mir-10-P3c  Laf-Mir-10-P3d 
Orthologues Aae-Mir-10-P2  Aca-Mir-10-P2c  Adi-Mir-10  Aga-Mir-10-P2  Agr-Mir-10-P2  Ami-Mir-10-P2c  Asp-Mir-10  Bfl-Mir-10-P2-v1  Bge-Mir-10-P2  Bko-Mir-10-P2  Bla-Mir-10-P2-v1  Bpl-Mir-10-P2  Bta-Mir-10-P2c  Cbr-Mir-10-P2  Cel-Mir-10-P2  Cfa-Mir-10-P2c  Cin-Mir-10-P2  Cja-Mir-10-P2c  Cli-Mir-10-P2c  Cmi-Mir-10-P2c  Cpi-Mir-10-P2c  Cpo-Mir-10-P2c  Cte-Mir-10-P2  Dan-Mir-10-P2  Dgr-Mir-10-P2  Dlo-Mir-10-P2  Dma-Mir-10-P2  Dme-Mir-10-P2  Dmo-Mir-10-P2  Dno-Mir-10-P2c  Dpu-Mir-10-P2  Dre-Mir-10-P2c1  Dre-Mir-10-P2c2  Dsi-Mir-10-P2  Dya-Mir-10-P2  Eba-Mir-10-P2  Eca-Mir-10-P2c  Ete-Mir-10-P2c  Gga-Mir-10-P2c  Gja-Mir-10-P2c  Gmo-Mir-10-P2c2  Gpa-Mir-10-P2  Gsp-Mir-10-P2  Hru-Mir-10-P2  Hsa-Mir-10-P2c  Isc-Mir-10-P2  Lan-Mir-10-P2  Lch-Mir-10-P2c  Lgi-Mir-10-P2  Lhy-Mir-10-P2  Llo-Mir-10-P2  Loc-Mir-10-P2c  Mal-Mir-10-P2c2  Mgi-Mir-10-P2  Mml-Mir-10-P2c  Mmr-Mir-10-P2c  Mmu-Mir-10-P2c  Mom-Mir-10-P2  Mun-Mir-10-P2c  Neu-Mir-10-P2c  Npo-Mir-10-P2  Nve-Mir-10  Oan-Mir-10-P2c  Obi-Mir-10-P2  Ocu-Mir-10-P2c  Ofu-Mir-10-P2  Ovu-Mir-10-P2  Pab-Mir-10-P2c  Pau-Mir-10-P2  Pbv-Mir-10-P2c  Pca-Mir-10-P2  Pdu-Mir-10-P2  Pfl-Mir-10-P2  Ple-Mir-10-P2  Pmi-Mir-10-P2  Pve-Mir-10-P2  Rno-Mir-10-P2c  Rph-Mir-10-P2  Sha-Mir-10-P2c  Sko-Mir-10-P2  Snu-Mir-10-P2  Spt-Mir-10-P2c  Sto-Mir-10-P2c  Tca-Mir-10-P2  Tgu-Mir-10-P2c  Tur-Mir-10-P2  Xbo-Mir-10-P2  Xbo-Mir-10-P2-as  Xla-Mir-10-P2c3  Xla-Mir-10-P2c4  Xtr-Mir-10-P2c 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Eumetazoa
Genome context
(GCA_000001905.1_Loxafr3.0)		 GL010040.1: 39383953-39384011 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Mir-10-P2c)		 Let-7-P1c GL010040.1: 39383200-39383266 [-] UCSC Ensembl
Mir-10-P2c GL010040.1: 39383953-39384011 [-] UCSC Ensembl
Seed ACCCGUA
Precursor
(pre-Mir +30nt flank)		 
AGCCCAUGUGAGAUGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGAACCGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUAAUCUGACAAAACUCUGU
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Structure
        10         20         30        40        50         
AGCCCAUGUGAGAUGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UGUCUCAAAACAGUCUAA   U^         C         UC   C      GCCAAG 
       110       100        90        80        70        60
Deep sequencing
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CommentBased on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.
3' NTU Yes
MotifsUG at 5p(-14), UGUG in loop
Tissue expression
- +
Wh
Mature sequence

Laf-Mir-10-P2c_5p
mirBase accessionNone
Sequence 
0- AACCCGUAGAUCCGAUCUUGUG -22
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Star sequence

Laf-Mir-10-P2c_3p*
mirBase accessionNone
Sequence 
37- CAAGCUCGCUUCUAUGGGUCUG -59
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