Mir-10-P2c

MirGeneDB ID

Bta-Mir-10-P2c

Family name

MIR-10 (all species)

Species

Cow (Bos taurus)

MiRBase ID

bta-mir-99a

Paralogues

Bta-Mir-10-P1b-v1 Bta-Mir-10-P1c-v1 Bta-Mir-10-P2b Bta-Mir-10-P2d Bta-Mir-10-P3b Bta-Mir-10-P3c Bta-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bpl-Mir-10-P2 Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2c Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmr-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCF_002263795.1_ARS-UCD1.2_BTA)

NC_037328.1: 20435353-20435411 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P3c NC_037328.1: 20385513-20385573 [-] UCSC Ensembl
Let-7-P1c NC_037328.1: 20434624-20434690 [-] UCSC Ensembl
Mir-10-P2c NC_037328.1: 20435353-20435411 [-] UCSC Ensembl

Seed

ACCCGUA

Precursor
(pre-Mir +30nt flank)

AGCCCACGUGAGACGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACCGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUAAUCUGACAAAAUGCAAU

Get precursor sequence

Structure

        10         20         30        40        50         
AGCCCACGUGAGACGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAACGUAAAACAGUCUAA   U^         C         UC   C      GCCAGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Ad	Bo	Br	Ce	Co	Co	De	Fe	He	Hy	Ir	Ki	La	Lo	Mi	No	Op	Or	Pe	Re	Su	Te

Mature sequence

Bta-Mir-10-P2c_5p

mirBase accession

MIMAT0003537

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

Get sequence

Proposed targets

TargetScanVert: bta-miR-99a-5p

Star sequence

Bta-Mir-10-P2c_3p*

mirBase accession

MIMAT0012533

Sequence

37- CAAGCUCGCUUCUAUGGGUCUG -59

Get sequence

Proposed targets

TargetScanVert: bta-miR-99a-3p