Mir-10-P2c

MirGeneDB ID

Mmr-Mir-10-P2c

Family name

MIR-10 (all species)

Species

Gray mouse lemur (Microcebus murinus)

MiRBase ID

mmr-mir-99a

Paralogues

Mmr-Mir-10-P1b-v1 Mmr-Mir-10-P1c-v1 Mmr-Mir-10-P2b Mmr-Mir-10-P2d Mmr-Mir-10-P3b Mmr-Mir-10-P3c Mmr-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bpl-Mir-10-P2 Bta-Mir-10-P2c Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Eca-Mir-10-P2c Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCA_000165445.3_Mmur_3.0_genomic)

CM007691.1: 18654596-18654654 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P2c CM007691.1: 18654596-18654654 [+] UCSC Ensembl
Let-7-P1c CM007691.1: 18655332-18655398 [+] UCSC Ensembl
Mir-10-P3c CM007691.1: 18700376-18700436 [+] UCSC Ensembl

Seed

ACCCGUA

Precursor
(pre-Mir +30nt flank)

AGCCCAUGUGAGAUGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUAAAGUGGACCGCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGCGGUAAUCUGACAAAAUGCUAU

Get precursor sequence

Structure

        10         20         30        40        50         
AGCCCAUGUGAGAUGUU-   -|         A         UC   U      GUAAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAUCGUAAAACAGUCUAA   C^         C         UC   C      GCCAGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14)

Tissue expression

Mu	Mu	Mu	Mu	Mu	Mu	Mu	Mu

Mature sequence

Mmr-Mir-10-P2c_5p

mirBase accession

MIMAT0049202

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

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Star sequence

Mmr-Mir-10-P2c_3p*

mirBase accession

None

Sequence

37- CAAGCUCGCUUCUAUGGGUCUG -59

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