Mir-10-P2c

MirGeneDB ID

Eca-Mir-10-P2c

Family name

MIR-10 (all species)

Species

Horse (Equus caballus)

MiRBase ID

eca-mir-99a-2

Paralogues

Eca-Mir-10-P1b-v1 Eca-Mir-10-P1c-v1 Eca-Mir-10-P2b Eca-Mir-10-P2d Eca-Mir-10-P3b Eca-Mir-10-P3c Eca-Mir-10-P3d

Orthologues

Aae-Mir-10-P2 Aca-Mir-10-P2c Adi-Mir-10 Aga-Mir-10-P2 Agr-Mir-10-P2 Ami-Mir-10-P2c Asp-Mir-10 Bfl-Mir-10-P2-v1 Bge-Mir-10-P2 Bko-Mir-10-P2 Bla-Mir-10-P2-v1 Bpl-Mir-10-P2 Bta-Mir-10-P2c Cbr-Mir-10-P2 Cel-Mir-10-P2 Cfa-Mir-10-P2c Cin-Mir-10-P2 Cja-Mir-10-P2c Cli-Mir-10-P2c Cmi-Mir-10-P2c Cpi-Mir-10-P2c Cpo-Mir-10-P2c Cte-Mir-10-P2 Dan-Mir-10-P2 Dgr-Mir-10-P2 Dlo-Mir-10-P2 Dma-Mir-10-P2 Dme-Mir-10-P2 Dmo-Mir-10-P2 Dno-Mir-10-P2c Dpu-Mir-10-P2 Dre-Mir-10-P2c1 Dre-Mir-10-P2c2 Dsi-Mir-10-P2 Dya-Mir-10-P2 Eba-Mir-10-P2 Ete-Mir-10-P2c Gga-Mir-10-P2c Gja-Mir-10-P2c Gmo-Mir-10-P2c2 Gpa-Mir-10-P2 Gsp-Mir-10-P2 Hru-Mir-10-P2 Hsa-Mir-10-P2c Isc-Mir-10-P2 Laf-Mir-10-P2c Lan-Mir-10-P2 Lch-Mir-10-P2c Lgi-Mir-10-P2 Lhy-Mir-10-P2 Llo-Mir-10-P2 Loc-Mir-10-P2c Mal-Mir-10-P2c2 Mgi-Mir-10-P2 Mml-Mir-10-P2c Mmr-Mir-10-P2c Mmu-Mir-10-P2c Mom-Mir-10-P2 Mun-Mir-10-P2c Neu-Mir-10-P2c Npo-Mir-10-P2 Nve-Mir-10 Oan-Mir-10-P2c Obi-Mir-10-P2 Ocu-Mir-10-P2c Ofu-Mir-10-P2 Ovu-Mir-10-P2 Pab-Mir-10-P2c Pau-Mir-10-P2 Pbv-Mir-10-P2c Pca-Mir-10-P2 Pdu-Mir-10-P2 Pfl-Mir-10-P2 Ple-Mir-10-P2 Pmi-Mir-10-P2 Pve-Mir-10-P2 Rno-Mir-10-P2c Rph-Mir-10-P2 Sha-Mir-10-P2c Sko-Mir-10-P2 Snu-Mir-10-P2 Spt-Mir-10-P2c Sto-Mir-10-P2c Tca-Mir-10-P2 Tgu-Mir-10-P2c Tur-Mir-10-P2 Xbo-Mir-10-P2 Xbo-Mir-10-P2-as Xla-Mir-10-P2c3 Xla-Mir-10-P2c4 Xtr-Mir-10-P2c

Node of Origin (locus)

Gnathostomata

Node of Origin (family)

Eumetazoa

Genome context
(GCA_002863925.1_EquCab3.0)

CM009173.1: 16008731-16008789 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-10-P2c)

Mir-10-P2c CM009173.1: 16008731-16008789 [+] UCSC Ensembl
Let-7-P1c CM009173.1: 16009464-16009530 [+] UCSC Ensembl
Mir-10-P3c CM009173.1: 16052916-16052976 [+] UCSC Ensembl

Seed

ACCCGUA

Precursor
(pre-Mir +30nt flank)

AGCUCAUGUGAGAUGUUGCCCAUUGGCAUAAACCCGUAGAUCCGAUCUUGUGGUGAAGUGGACCUCACAAGCUCGCUUCUAUGGGUCUGUGUCAGUGUGGUAAUCUGACAAAAUGCUAU

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Structure

        10         20         30        40        50         
AGCUCAUGUGAGAUGUU-   -|         A         UC   U      GUGAAG 
                  GCC CAUUGGCAUA ACCCGUAGA  CGA CUUGUG      \
                  UGG GUGACUGUGU UGGGUAUCU  GCU GAACAC      U
UAUCGUAAAACAGUCUAA   U^         C         UC   C      UCCAGG 
       110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

Based on the 3' DcRNA reads in human (P2b) and platypus (P2c) it appears that this is a Group 2 miRNA.

3' NTU

Yes

Motifs

UG at 5p(-14), UGUG in loop

Tissue expression

Ps	Bo	Ca	Em	En	En	En	En	En	En	En	Gl	He	He	Ho	Im	Ki	Li	Lo	Lu	Ma	Ma	Mi	Pl	Sp	Te	Tr	Ut	Ut	Yo

Mature sequence

Eca-Mir-10-P2c_5p

mirBase accession

MIMAT0013184

Sequence

0- AACCCGUAGAUCCGAUCUUGUG -22

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Star sequence

Eca-Mir-10-P2c_3p*

mirBase accession

None

Sequence

37- CAAGCUCGCUUCUAUGGGUCUG -59

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