MirGeneDB 3.0
MirGeneDB ID

Bla-Mir-22-P2a

Family name MIR-22 (all species)
Species European lancelet (Branchiostoma lanceolatum)
MiRBase ID
Paralogues Bla-Mir-22-o3a1a  Bla-Mir-22-o3a1b  Bla-Mir-22-o3a1c  Bla-Mir-22-o3a1d  Bla-Mir-22-o3a2a  Bla-Mir-22-o3a2b  Bla-Mir-22-o3a3  Bla-Mir-22-o3b1  Bla-Mir-22-o3b2  Bla-Mir-22-o3b3  Bla-Mir-22-o3c1  Bla-Mir-22-o3c2  Bla-Mir-22-P1  Bla-Mir-22-P2b  Bla-Mir-22-P2c 
Orthologues Aae-Mir-22-P2  Aga-Mir-22-P2  Agr-Mir-22-P2  Asu-Mir-22-P2  Bfl-Mir-22-P2a  Bge-Mir-22-P2  Cbr-Mir-22-P2-v1  Cel-Mir-22-P2  Csc-Mir-22-P2  Cte-Mir-22-P2  Dan-Mir-22-P2  Dlo-Mir-22-P2  Dma-Mir-22-P2  Dme-Mir-22-P2  Dmo-Mir-22-P2  Dpu-Mir-22-P2  Dsi-Mir-22-P2  Dya-Mir-22-P2  Eba-Mir-22-P2  Esc-Mir-22-P2  Gpa-Mir-22-P2  Hme-Mir-22-P2  Hru-Mir-22-P2  Isc-Mir-22-P2  Lan-Mir-22-P2  Lgi-Mir-22-P2  Lhy-Mir-22-P2  Llo-Mir-22-P2  Mgi-Mir-22-P2  Mom-Mir-22-P2  Npo-Mir-22-P2  Ovu-Mir-22-P2  Pau-Mir-22-P2  Pca-Mir-22-P2  Pdu-Mir-22-P2  Pfl-Mir-22-P2  Pmi-Mir-22-P2  Pve-Mir-22-P2  Rph-Mir-22-P2  Sko-Mir-22-P2  Snu-Mir-22-P2  Spu-Mir-22-P2  Tca-Mir-22-P2-v1  Tur-Mir-22-P2  War-Mir-22-P2 
Node of Origin (locus) Branchiostoma
Node of Origin (family) Bilateria
Genome context
(BraLan2)		 Sc0000017: 1361498-1361557 [-] Ensembl
Clustered miRNAs
(< 50kb from Mir-22-P2a)		 Mir-22-P2b Sc0000017: 1346304-1346363 [-] Ensembl
Mir-22-P2a Sc0000017: 1361498-1361557 [-] Ensembl
Seed UGAUCAG
Precursor
(pre-Mir +30nt flank)		 
CAGAAGUAAGCAAAUCUGGUCUUCUCGUCCCUGAUCAGCCCGGAAGCUGUUACGUCACUUCCGCUGUAUCAGCUCCAGCGCUGAUCAGUGACGCGAUGACUUAUAAUCAACUACGUCAGA
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Structure
        10          20        30        40         50         
CAGAAGUAAGCAAAUCU--    U  U    C         CC-|  A    U  CGUCAC 
                   GGUC UC CGUC CUGAUCAGC   GGA GCUG UA      U
                   UCAG AG GCAG GACUAGUCG   CCU CGAC AU      U
AGACUGCAUCAACUAAUAU    U  C    U         CGA^  -    U  GUCGCC 
.       110       100        90        80         70        60
Deep sequencing
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CommentIt is unclear if this paralogue group represents the ancestral Mir-22-P2 gene that is seed shifted or a new paralogue derived from the ancestral P1 gene. It is also unclear if this gene is orthologous to the Mir-22-o2 gene in ambulacrarians.
3' NTU Yes
MotifsUG at 5p(-14), CNNC at 3p(+17)
Tissue expression
- +
Ad Ad Em Em Em Em
Mature sequence

Bla-Mir-22-P2a_5p
mirBase accessionNone
Sequence 
0- CUGAUCAGCCCGGAAGCUGUUA -22
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Co-mature sequence

Bla-Mir-22-P2a_3p
mirBase accessionNone
Sequence 
38- UCAGCUCCAGCGCUGAUCAGUG -60
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