Mir-8-P3a

MirGeneDB ID

Hsa-Mir-8-P3a

Family name

MIR-8 (all species)

Species

Human (Homo sapiens)

MiRBase ID

hsa-mir-429

Paralogues

Hsa-Mir-8-P1a Hsa-Mir-8-P1b Hsa-Mir-8-P2a Hsa-Mir-8-P2b

Orthologues

Aae-Mir-8 Aca-Mir-8-P3a Aga-Mir-8 Agr-Mir-8 Ami-Mir-8-P3a Asu-Mir-8 Bfl-Mir-8-P3 Bge-Mir-8 Bko-Mir-8 Bla-Mir-8-P3 Bpl-Mir-8 Bta-Mir-8-P3a Cbr-Mir-8 Cel-Mir-8 Cfa-Mir-8-P3a Cja-Mir-8-P3a Cli-Mir-8-P3a Cmi-Mir-8-P3a Cpi-Mir-8-P3a Cpo-Mir-8-P3a Csc-Mir-8 Cte-Mir-8 Dan-Mir-8 Dgr-Mir-8 Dlo-Mir-8 Dma-Mir-8 Dme-Mir-8 Dmo-Mir-8 Dno-Mir-8-P3a Dpu-Mir-8 Dre-Mir-8-P3a Dsi-Mir-8 Dya-Mir-8 Eba-Mir-8 Eca-Mir-8-P3a Egr-Mir-8 Esc-Mir-8 Ete-Mir-8-P3a Gga-Mir-8-P3a Gja-Mir-8-P3a Gmo-Mir-8-P3a Gpa-Mir-8 Gsa-Mir-8 Hme-Mir-8 Hru-Mir-8 Isc-Mir-8 Laf-Mir-8-P3a Lan-Mir-8 Lch-Mir-8-P3a Lgi-Mir-8 Lhy-Mir-8 Llo-Mir-8 Loc-Mir-8-P3a Mal-Mir-8-P3a Mdo-Mir-8-P3a Mgi-Mir-8 Mml-Mir-8-P3a Mmr-Mir-8-P3a Mmu-Mir-8-P3a Mom-Mir-8 Mun-Mir-8-P3a Neu-Mir-8-P3a Npo-Mir-8 Oan-Mir-8-P3a Obi-Mir-8 Ocu-Mir-8-P3a Ofu-Mir-8 Ovu-Mir-8 Pab-Mir-8-P3a Pau-Mir-8 Pbv-Mir-8-P3a Pca-Mir-8 Pdu-Mir-8 Pfl-Mir-8 Pmi-Mir-8 Pve-Mir-8 Rno-Mir-8-P3a Rph-Mir-8 Sha-Mir-8-P3a Sko-Mir-8 Sma-Mir-8 Snu-Mir-8 Spt-Mir-8-P3a Spu-Mir-8 Sto-Mir-8-P3a Tca-Mir-8 Tni-Mir-8-P3a Tur-Mir-8 War-Mir-8 Xla-Mir-8-P3a1 Xla-Mir-8-P3a2 Xtr-Mir-8-P3a

Node of Origin (locus)

Vertebrata

Node of Origin (family)

Nephrozoa

Genome context
(hg38)

chr1: 1169020-1169076 [+] UCSC Ensembl

Clustered miRNAs
(< 50kb from Mir-8-P3a)

Mir-8-P1a chr1: 1167124-1167182 [+] UCSC Ensembl
Mir-8-P2a chr1: 1167878-1167938 [+] UCSC Ensembl
Mir-8-P3a chr1: 1169020-1169076 [+] UCSC Ensembl

Seed

AAUACUG

Precursor
(pre-Mir +30nt flank)

GGCCACCCACACCACCGCCGGCCGAUGGGCGUCUUACCAGACAUGGUUAGACCUGGCCCUCUGUCUAAUACUGUCUGGUAAAACCGUCCAUCCGCUGCCUGAUCACCGUUAGAGGAG

Get precursor sequence

Structure

        10          20        30         40        50       
GGCCACCCACACCACCGC--    C        UC-|         UG      CCUGG 
                    CGGC GAUGGGCG   UUACCAGACA  GUUAGA     C
                    GUCG CUACCUGC   AAUGGUCUGU  UAAUCU     C
GAGGAGAUUGCCACUAGUCC    C        CAA^         CA      GUCUC 
     110       100        90        80        70        60

Deep sequencing

Go to detailed chart

Comment

There is a second Drosha cut +1 on both arms.

3' NTU

Motifs

CNNC at 3p(+17)

Tissue expression

Dc	Dc	Dr	Dr	Xp	Xp	Bl	Br	Br	Ce	Ce	Co	Fo	He	Ki	Le	Li	Li	Lu	Pa	Pl	Pl	Sk	Sk	Sk	Sm	Sp	Sp	St	Te	Th	Ut

Star sequence

Hsa-Mir-8-P3a_5p*

mirBase accession

None

Sequence

0- GUCUUACCAGACAUGGUUAGA -21

Get sequence

Mature sequence

Hsa-Mir-8-P3a_3p

mirBase accession

MIMAT0001536

Sequence

35- UAAUACUGUCUGGUAAAACCGU -57

Get sequence

Proposed targets

microrna.org: MIMAT0001536
TargetScanVert: hsa-miR-429
TargetMiner: hsa-miR-429
miRDB: MIMAT0001536