Let-7-P2b4b

MirGeneDB ID

Dre-Let-7-P2b4b

Family name

LET-7 (all species)

Species

Zebrafish (Danio rerio)

MiRBase ID

dre-let-7a-6

Paralogues

Dre-Let-7-P1b1 Dre-Let-7-P1b2 Dre-Let-7-P1c1 Dre-Let-7-P1c2 Dre-Let-7-P1d1 Dre-Let-7-P1d2 Dre-Let-7-P2a1a Dre-Let-7-P2a2a Dre-Let-7-P2a2b Dre-Let-7-P2a3a Dre-Let-7-P2a3b Dre-Let-7-P2a4a Dre-Let-7-P2a4b Dre-Let-7-P2b1a Dre-Let-7-P2b2a Dre-Let-7-P2b2b Dre-Let-7-P2b3a Dre-Let-7-P2b4a Dre-Let-7-P2c2b Dre-Let-7-P2c3

Orthologues

Aae-Let-7 Aca-Let-7-P2b4 Aga-Let-7 Agr-Let-7 Ami-Let-7-P2b4 Bge-Let-7 Bko-Let-7 Bpl-Let-7 Cli-Let-7-P2b4 Cmi-Let-7-P2b4 Cpi-Let-7-P2b4 Cte-Let-7 Dan-Let-7 Dlo-Let-7 Dma-Let-7 Dme-Let-7 Dmo-Let-7 Dpu-Let-7 Dsi-Let-7 Dya-Let-7 Eba-Let-7 Egr-Let-7 Esc-Let-7 Gga-Let-7-P2b4 Gja-Let-7-P2b4 Gmo-Let-7-P2b4a Gmo-Let-7-P2b4b Gpa-Let-7 Gsa-Let-7 Gsp-Let-7 Hme-Let-7 Hmi-Let-7 Hru-Let-7 Isc-Let-7 Lan-Let-7 Lch-Let-7-P2b4 Lgi-Let-7 Lhy-Let-7 Llo-Let-7 Loc-Let-7-P2b4 Mal-Let-7-P2b4a Mal-Let-7-P2b4b Mgi-Let-7 Mom-Let-7 Mun-Let-7-P2b4 Npo-Let-7 Oan-Let-7-P2b4 Obi-Let-7 Ofu-Let-7 Ovu-Let-7 Pau-Let-7 Pbv-Let-7-P2b4 Pca-Let-7 Pcr-Let-7 Pdu-Let-7 Pfl-Let-7 Ple-Let-7 Pmi-Let-7 Pve-Let-7 Rph-Let-7 Sko-Let-7 Sma-Let-7 Sne-Let-7 Snu-Let-7 Spt-Let-7-P2b4 Spu-Let-7 Sro-Let-7 Tca-Let-7 Tgu-Let-7-P2b4 Tni-Let-7-P2b4a Tni-Let-7-P2b4b Tur-Let-7 War-Let-7 Xbo-Let-7

Node of Origin (locus)

Clupeocephala

Node of Origin (family)

Bilateria

Genome context
(danRer11)

chr6: 54506483-54506558 [-] UCSC Ensembl

Clustered miRNAs
(< 50kb from Let-7-P2b4b)

Let-7-P2b4b chr6: 54506483-54506558 [-] UCSC Ensembl
Let-7-P2a4b chr6: 54507105-54507176 [-] UCSC Ensembl

Seed

GAGGUAG

Precursor
(pre-Mir +30nt flank)

UCCACAGUGAACCUGUGUGUUUCUUCAAGGUGAGGUAGUAGGUUGUAUAGUUUGUGGGAAGGAUCACAUCCUAUUCAGGUGAUAACUAUACAGUCUAUUGCCUUCCCUGAGAGACACAAUGACCACGAGUGAAAAC

Get precursor sequence

Structure

        10           20        30        40        50        60        
UCCACAGUGAACCUGUG---|       CA   UG         GU         UGUGGGAAGGAUCAC 
                    UGUUUCUU  AGG  AGGUAGUAG  UGUAUAGUU               \
                    ACAGAGAG  UCC  UCCGUUAUC  ACAUAUCAA               A
CAAAAGUGAGCACCAGUAAC^       --   CU         UG         UAGUGGACUUAUCCU 
    130       120       110         100        90        80        70

Deep sequencing

Go to detailed chart

3' NTU

Yes

Motifs

CNNC at 3p(+17), UGUG in loop

Tissue expression

Br	Br	Em	Ey	Gu	Gu	He	Li	Li	Ov	Te

Mature sequence

Dre-Let-7-P2b4b_5p

mirBase accession

MIMAT0001759

Sequence

0- UGAGGUAGUAGGUUGUAUAGUU -22

Get sequence

Proposed targets

TargetScanFish: dre-let-7a

Star sequence

Dre-Let-7-P2b4b_3p*

mirBase accession

None

Sequence

55- CUAUACAGUCUAUUGCCUUCC -76

Get sequence