MirGeneDB 3.0

MirGeneDB ID

Aca-Let-7-P2b4

Family name LET-7 (all species)
Species Green anole lizard (Anolis carolinensis)
MiRBase ID
Paralogues Aca-Let-7-P1b  Aca-Let-7-P1c  Aca-Let-7-P1d  Aca-Let-7-P2a1  Aca-Let-7-P2a2  Aca-Let-7-P2a3  Aca-Let-7-P2a4  Aca-Let-7-P2b1  Aca-Let-7-P2b2  Aca-Let-7-P2b3  Aca-Let-7-P2c1  Aca-Let-7-P2c2  Aca-Let-7-P2c3 
Orthologues Aae-Let-7  Aga-Let-7  Agr-Let-7  Ami-Let-7-P2b4  Bge-Let-7  Bko-Let-7  Bpl-Let-7  Cli-Let-7-P2b4  Cmi-Let-7-P2b4  Cpi-Let-7-P2b4  Cte-Let-7  Dan-Let-7  Dlo-Let-7  Dma-Let-7  Dme-Let-7  Dmo-Let-7  Dpu-Let-7  Dre-Let-7-P2b4a  Dre-Let-7-P2b4b  Dsi-Let-7  Dya-Let-7  Eba-Let-7  Egr-Let-7  Esc-Let-7  Gga-Let-7-P2b4  Gja-Let-7-P2b4  Gmo-Let-7-P2b4a  Gmo-Let-7-P2b4b  Gpa-Let-7  Gsa-Let-7  Gsp-Let-7  Hme-Let-7  Hmi-Let-7  Hru-Let-7  Isc-Let-7  Lan-Let-7  Lch-Let-7-P2b4  Lgi-Let-7  Lhy-Let-7  Llo-Let-7  Loc-Let-7-P2b4  Mal-Let-7-P2b4a  Mal-Let-7-P2b4b  Mgi-Let-7  Mom-Let-7  Mun-Let-7-P2b4  Npo-Let-7  Oan-Let-7-P2b4  Obi-Let-7  Ofu-Let-7  Ovu-Let-7  Pau-Let-7  Pbv-Let-7-P2b4  Pca-Let-7  Pcr-Let-7  Pdu-Let-7  Pfl-Let-7  Ple-Let-7  Pmi-Let-7  Pve-Let-7  Rph-Let-7  Sko-Let-7  Sma-Let-7  Sne-Let-7  Snu-Let-7  Spt-Let-7-P2b4  Spu-Let-7  Sro-Let-7  Tca-Let-7  Tgu-Let-7-P2b4  Tni-Let-7-P2b4a  Tni-Let-7-P2b4b  Tur-Let-7  War-Let-7  Xbo-Let-7 
Node of Origin (locus) Gnathostomata
Node of Origin (family) Bilateria
Genome context
(anoCar2)
4: 123683315-123683391 [-] UCSC Ensembl
Clustered miRNAs
(< 50kb from Let-7-P2b4)
Let-7-P2b4 4: 123683315-123683391 [-] UCSC Ensembl
Let-7-P2a4 4: 123683614-123683684 [-] UCSC Ensembl
Seed GAGGUAG
Precursor
(pre-Mir +30nt flank)
AUAUGAAGCCUCUAUCUUGCUUUGUGGAGGUGAGGUAGUAGGUUGUAUAGUUUGUGGGAGGGAUUACAUCCCAUUUCAGGUGAUAACUAUACAGUCUAUUGCCUUCCUUAAGGAGCAACAAAUCUGGCUUAGGAGCA
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Structure
        10           20        30        40        50        60        
AUAUGAAGCCUCUAUCU---|     GUG    U          GU         UGUGGGAGGGAUUAC 
                    UGCUUU   GAGG GAGGUAGUAG  UGUAUAGUU               A
                    ACGAGG   UUCC UUCCGUUAUC  ACAUAUCAA               U
ACGAGGAUUCGGUCUAAACA^     AA-    -          UG         UAGUGGACUUUACCC 
     130       120       110         100        90        80        70
Deep sequencing
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CommentAlthough all Let-7-P13s have a templated "T" all other vertebrate Let-7-P4 through P14s are Group 2 miRNAs and where studied all 3' terminal "U"s are post-transcriptionally added to the transcript and thus P13 is also considered a Group 2 miRNA.
3' NTU Yes
MotifsUGUG in loop
Tissue expression
- +
Sk Ta Ta To Wh
Mature sequence

Aca-Let-7-P2b4_5p

mirBase accessionNone
Sequence
0- UGAGGUAGUAGGUUGUAUAGUU -22
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Star sequence

Aca-Let-7-P2b4_3p*

mirBase accessionNone
Sequence
56- CUAUACAGUCUAUUGCCUUCC -77
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